Complete sequence of the first chimera genome constructed by cloning the whole genome of Synechocystis strain PCC6803 into the Bacillus subtilis 168 genome

Satoru Watanabe, Yuh Shiwa, Mitsuhiro Itaya, Hirofumi Yoshikawa

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11 Citations (Scopus)

Abstract

Genome synthesis of existing or designed genomes is made feasible by the first successful cloning of a cyanobacterium, Synechocystis PCC6803, in Gram-positive, endospore-forming Bacillus subtilis. Whole-genome sequence analysis of the isolate and parental B. subtilis strains provides clues for identifying single nucleotide polymorphisms (SNPs) in the 2 complete bacterial genomes in one cell.

Original languageEnglish
Pages (from-to)7007
Number of pages1
JournalJournal of Bacteriology
Volume194
Issue number24
DOIs
Publication statusPublished - 2012 Oct 1

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ASJC Scopus subject areas

  • Microbiology
  • Molecular Biology

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