Complications after spinal fixation surgery for osteoporotic vertebral collapse with neurological deficits: Japan Association of Spine Surgeons with ambition multicenter study

Yusuke Sakai, Takashi Kaito, Shota Takenaka, Tomoya Yamashita, Takahiro Makino, Naobumi Hosogane, Kenya Nojiri, Satoshi Suzuki, Eijiro Okada, Kota Watanabe, Haruki Funao, Norihiro Isogai, Seiji Ueda, Tomohiro Hikata, Yuta Shiono, Kei Watanabe, Keiichi Katsumi, Hiroyasu Fujiwara, Yukitaka Nagamoto, Hidetomi TeraiKoji Tamai, Yuji Matsuoka, Hidekazu Suzuki, Hirosuke Nishimura, Atsushi Tagami, Shuta Yamada, Shinji Adachi, Seiji Ohtori, Sumihisa Orita, Takeo Furuya, Toshitaka Yoshii, Shuta Ushio, Gen Inoue, Masayuki Miyagi, Wataru Saito, Shiro Imagama, Kei Ando, Daisuke Sakai, Tadashi Nukaga, Katsuhito Kiyasu, Atsushi Kimura, Hirokazu Inoue, Atsushi Nakano, Katsumi Harimaya, Toshio Doi, Kenichi Kawaguchi, Nobuhiko Yokoyama, Hidekazu Oishi, Shota Ikegami, Toshimasa Futatsugi, Masayuki Shimizu, Kenichiro Kakutani, Takashi Yurube, Masashi Oshima, Hiroshi Uei, Yasuchika Aoki, Masahiko Takahata, Akira Iwata, Shoji Seki, Hideki Murakami, Katsuhito Yoshioka, Hirooki Endo, Michio Hongo, Kazuyoshi Nakanishi, Tetsuya Abe, Toshinori Tsukanishi, Ken Ishii

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Abstract

Background: There have been few reports on the incidence and risk factors of the complications after spinal fixation surgery for osteoporotic vertebral collapse (OVC) with neurological deficits. This study aimed to identify the incidence and risk factors of the complications after OVC surgery. Methods: In this retrospective multicenter study, a total of 403 patients (314 women and 89 men; mean age 73.8 years) who underwent spinal fixation surgery for OVC with neurological deficits between 2005 and 2014 were enrolled. Data on patient demographics were collected, including age, sex, body mass index, smoking, steroid use, medical comorbidities, and surgical procedures. All postoperative complications that occurred within 6 weeks were recorded. Patients were classified into two groups, namely, complication group and no complication group, and risk factors for postoperative complications were investigated by univariate and multivariate analyses. Results: Postoperative complications occurred in 57 patients (14.1%), and the most common complication was delirium (5.7%). In the univariate analysis, the complication group was found to be older (p = 0.039) and predominantly male (p = 0.049), with higher occurrence rate of liver disease (p = 0.001) and Parkinson's disease (p = 0.039) compared with the no-complication group. In the multivariate analysis, the significant independent risk factors were age (p = 0.021; odds ratio [OR] 1.051, 95% confidence interval [CI] 1.007–1.097), liver disease (p < 0.001; OR 8.993, 95% CI 2.882–28.065), and Parkinson's disease (p = 0.009; OR 3.636, 95% CI 1.378–9.599). Conclusions: Complications after spinal fixation surgery for OVC with neurological deficits occurred in 14.1%. Age, liver disease, and Parkinson's disease were demonstrated to be independent risk factors for postoperative complications.

Original languageEnglish
Pages (from-to)985-990
Number of pages6
JournalJournal of Orthopaedic Science
Volume24
Issue number6
DOIs
Publication statusPublished - 2019 Nov

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ASJC Scopus subject areas

  • Surgery
  • Orthopedics and Sports Medicine

Cite this

Sakai, Y., Kaito, T., Takenaka, S., Yamashita, T., Makino, T., Hosogane, N., Nojiri, K., Suzuki, S., Okada, E., Watanabe, K., Funao, H., Isogai, N., Ueda, S., Hikata, T., Shiono, Y., Watanabe, K., Katsumi, K., Fujiwara, H., Nagamoto, Y., ... Ishii, K. (2019). Complications after spinal fixation surgery for osteoporotic vertebral collapse with neurological deficits: Japan Association of Spine Surgeons with ambition multicenter study. Journal of Orthopaedic Science, 24(6), 985-990. https://doi.org/10.1016/j.jos.2019.08.015