Three-component allylation and cyanation utilizing a ketone and an N-methoxyamine are reported. The high nucleophilicity of the N-methoxyamine and high electrophilicity of the corresponding iminium ion enable the concise synthesis of α-trisubstituted amines in a single step.
|Number of pages||4|
|Publication status||Published - 2012 Apr 20|
ASJC Scopus subject areas
- Physical and Theoretical Chemistry
- Organic Chemistry