Constituents of the seed of Malva verticillata. VII. Structural features and reticuloendothelial system-potentiating activity of MVS-I, the major neutral polysaccharide

N. Shimizu, H. Asahara, M. Tomoda, Ryoko Gonda, N. Ohara

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31 Citations (Scopus)

Abstract

The structural features of MVS-I, the major neutral polysaccharide isolated from the seeds of Malva verticillata L., were elucidated by controlled Smith degradation, methylation analysis, partial acid hydrolysis and enzymic degradation studies. It has a backbone chain composed of β-1,3-linked D-glucose and D-galactose residues having branches composed of α-1,5-linked L-arabinosyl β-1,4-linked D-galactose and of β-1,4-linked D-galactosyl β-1,3-linked D-glucose residues at position 6 of a part of D-galactose units as side chains. MVS-I showed remarkable reticuloendothelial system-potentiating activity in a carbon clearance test.

Original languageEnglish
Pages (from-to)2630-2632
Number of pages3
JournalChemical and Pharmaceutical Bulletin
Volume39
Issue number10
Publication statusPublished - 1991

Fingerprint

Malva
Mononuclear Phagocyte System
Galactose
Polysaccharides
Seed
Seeds
Glucose
Degradation
Methylation
Hydrolysis
Carbon
Acids

ASJC Scopus subject areas

  • Chemistry(all)
  • Organic Chemistry
  • Drug Discovery
  • Pharmacology

Cite this

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abstract = "The structural features of MVS-I, the major neutral polysaccharide isolated from the seeds of Malva verticillata L., were elucidated by controlled Smith degradation, methylation analysis, partial acid hydrolysis and enzymic degradation studies. It has a backbone chain composed of β-1,3-linked D-glucose and D-galactose residues having branches composed of α-1,5-linked L-arabinosyl β-1,4-linked D-galactose and of β-1,4-linked D-galactosyl β-1,3-linked D-glucose residues at position 6 of a part of D-galactose units as side chains. MVS-I showed remarkable reticuloendothelial system-potentiating activity in a carbon clearance test.",
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T1 - Constituents of the seed of Malva verticillata. VII. Structural features and reticuloendothelial system-potentiating activity of MVS-I, the major neutral polysaccharide

AU - Shimizu, N.

AU - Asahara, H.

AU - Tomoda, M.

AU - Gonda, Ryoko

AU - Ohara, N.

PY - 1991

Y1 - 1991

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