Constituents of the Seed of Malva verticillata: VII: 1) Structural Features and Reticuloendothelial System-Potentiating Activity of MVS-I, the Major Neutral Polysaccharide

Noriko Shimizu, Hatsuki Asahara, Masashi Tomoda, Ryoko Gonda, Naoko Ohara

Research output: Contribution to journalArticle

31 Citations (Scopus)

Abstract

The structural features of MVS-I, the major neutral polysaccharide isolated from the seeds of Malva verticillata L., were elucidated by controlled Smith degradation, methylation analysis, partial acid hydrolysis and enzymic degradation studies. It has a backbone chain composed of β -1,3-linked D-glucose and D-galactose residues having branches composed of α-l,5-linked L-arabinosyl β -l,4-linked D-galactose and of β -1,4-linked D-galactosyl β -1,3-linked D-glucose residues at position 6 of a part of D-galactose units as side chains. MVS-I showed remarkable reticuloendothelial system-potentiating activity in a carbon clearance test.

Original languageEnglish
Pages (from-to)2630-2632
Number of pages3
JournalChemical and Pharmaceutical Bulletin
Volume39
Issue number10
DOIs
Publication statusPublished - 1991

Keywords

  • MVS-I
  • Malva verticillata
  • Smith degradation
  • enzymic degradation
  • immunological activity
  • methylation analysis
  • partial hydrolysis
  • polysaccharide structure
  • reticuloendothelial system
  • seed

ASJC Scopus subject areas

  • Chemistry(all)
  • Drug Discovery

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