Constituents of the seed of Malva verticillata. VIII. Smith degradation of MVS-VI, the major acidic polysaccharide, and anti-complementary activity of products

M. Tomoda, H. Asahara, R. Gonda, K. Takada

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7 Citations (Scopus)

Abstract

The controlled Smith degradation of MVS-VI, the major acidic polysaccharide having remarkable anticomplementary activity isolated from the seeds of Malva verticillata L., was performed. Methylation analysis of both the primary and the secondary Smith degradation products indicated that the core structural features of MVS-VI include a backbone chain composed of β-1,3-linked D-galactose residues. The majority of galactose units in the backbone carry side chains composed of β-1,3- and β-1,6-linked D-galactosyl residues at position 6. The controlled Smith degradation products showed considerable anti-complementary activity.

Original languageEnglish
Pages (from-to)2219-2221
Number of pages3
JournalChemical and Pharmaceutical Bulletin
Volume40
Issue number8
Publication statusPublished - 1992
Externally publishedYes

Fingerprint

Malva
Galactose
Polysaccharides
Seed
Seeds
Degradation
Methylation

ASJC Scopus subject areas

  • Chemistry(all)
  • Organic Chemistry
  • Drug Discovery
  • Pharmacology

Cite this

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abstract = "The controlled Smith degradation of MVS-VI, the major acidic polysaccharide having remarkable anticomplementary activity isolated from the seeds of Malva verticillata L., was performed. Methylation analysis of both the primary and the secondary Smith degradation products indicated that the core structural features of MVS-VI include a backbone chain composed of β-1,3-linked D-galactose residues. The majority of galactose units in the backbone carry side chains composed of β-1,3- and β-1,6-linked D-galactosyl residues at position 6. The controlled Smith degradation products showed considerable anti-complementary activity.",
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T1 - Constituents of the seed of Malva verticillata. VIII. Smith degradation of MVS-VI, the major acidic polysaccharide, and anti-complementary activity of products

AU - Tomoda, M.

AU - Asahara, H.

AU - Gonda, R.

AU - Takada, K.

PY - 1992

Y1 - 1992

N2 - The controlled Smith degradation of MVS-VI, the major acidic polysaccharide having remarkable anticomplementary activity isolated from the seeds of Malva verticillata L., was performed. Methylation analysis of both the primary and the secondary Smith degradation products indicated that the core structural features of MVS-VI include a backbone chain composed of β-1,3-linked D-galactose residues. The majority of galactose units in the backbone carry side chains composed of β-1,3- and β-1,6-linked D-galactosyl residues at position 6. The controlled Smith degradation products showed considerable anti-complementary activity.

AB - The controlled Smith degradation of MVS-VI, the major acidic polysaccharide having remarkable anticomplementary activity isolated from the seeds of Malva verticillata L., was performed. Methylation analysis of both the primary and the secondary Smith degradation products indicated that the core structural features of MVS-VI include a backbone chain composed of β-1,3-linked D-galactose residues. The majority of galactose units in the backbone carry side chains composed of β-1,3- and β-1,6-linked D-galactosyl residues at position 6. The controlled Smith degradation products showed considerable anti-complementary activity.

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