Constituents of the Seed of Malva verticillata: VIII: 1) Smith Degradation of MVS-VI, the Major Acidic Polysaccharide, and Anti-complementary Activity of Products

Masashi Tomoda, Hatsuki Asahara, Ryoko Gonda, Katsutoshi Takada

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

The controlled Smith degradation of MVS-VI, the major acidic polysaccharide having remarkable anti-complementary activity isolated from the seeds of Malva verticillata L., was performed. Methylation analysis of both the primary and the secondary Smith degradation products indicated that the core structural features of MVS-VI include a backbone chain composed of /J-l,3-linked D-galactose residues. The majority of galactose units in the backbone carry side chains composed of /?-l,3- and /?-l,6-linked D-galactosyl residues at position 6. The controlled Smith degradation products showed considerable anti-complementary activity.

Original languageEnglish
Pages (from-to)2219-2221
Number of pages3
JournalChemical and Pharmaceutical Bulletin
Volume40
Issue number8
DOIs
Publication statusPublished - 1992

Keywords

  • MVS-VI
  • Malva verticillata
  • Smith degradation
  • anti-
  • complementary activity
  • partial hydrolysis
  • polysaccharide structure
  • seed

ASJC Scopus subject areas

  • Chemistry(all)
  • Drug Discovery

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