Continuous Nasogastric Infusion of Prostaglandin E2 in Ductus‐Dependent Congenital Heart Disease

Osamu Komiyama, Mitsuru Osano, Tadao Oikawa, Yoshiyuki Morikawa, Yoshifumi Kojima, Takayasu Murai, Jun Ishihara, Mitsuaki Tokumura, Nobuhiko Taguchi

Research output: Contribution to journalArticle

Abstract

Prostaglandin E2 (PGE2) was infused continuously through a nasogastric gavage tube in four infants with pulmonary atresia. The drug was given at a rate of 12.5–160 µg/kg/h. The duration of therapy was 7–123 days. The effects and side effects seen by this method were similar to those seen in the conventional multiple dose regimen. This method was an effective and simple way of maintaining the ductus arteriosus open, especially for a long period of time.

Original languageEnglish
Pages (from-to)553-556
Number of pages4
JournalPediatrics International
Volume30
Issue number5
DOIs
Publication statusPublished - 1988 Oct

Keywords

  • Blalock‐Taussig shunt
  • Ductus‐dependent congenital heart disease
  • Prostaglandin E1 and E2
  • Pulmonary atresia

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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    Komiyama, O., Osano, M., Oikawa, T., Morikawa, Y., Kojima, Y., Murai, T., Ishihara, J., Tokumura, M., & Taguchi, N. (1988). Continuous Nasogastric Infusion of Prostaglandin E2 in Ductus‐Dependent Congenital Heart Disease. Pediatrics International, 30(5), 553-556. https://doi.org/10.1111/j.1442-200X.1988.tb01579.x