TY - JOUR
T1 - Controlling the switching temperature of biodegradable shape memory polymers composed of stereocomplex polylactide / poly(D,L-lactide-co-ε-caprolactone) blends
AU - Hashimoto, Kenta
AU - Kurokawa, Naruki
AU - Hotta, Atsushi
N1 - Funding Information:
This work was supported in part by a Research grant from Nissin Sugar Manufacturing Scholarship Foundation to N.K., and Grant-in-aid for Science Research (A) (No. 19H00831 to A.H. and N.K), Grant-in-Aid for Challenging Exploratory Research (No. 19K22067 to A.H. and N.K), and Grant-in-Aid for Young Scientists (No. 20K15052 to N.K.) from Japan Society for the Promotion of Science (JSPS: “KAKENHI”).
Publisher Copyright:
© 2021 Elsevier Ltd
PY - 2021/10/26
Y1 - 2021/10/26
N2 - We synthesized new biodegradable shape-memory polymers (SMPs) by blending synthesized poly(D,L-lactide-co-ε-caprolactone) (PLCL) and stereocomplex polylactide (sc-PLA) to be used as biomaterials for medical devices. PLCL copolymers (Mn ∼80,000) with various monomer ratios (LA:CL) were synthesized by the bulk ring-opening polymerization. The glass transition temperature of the resulting PLCL copolymers could be well controlled from −3 °C to 60 °C, agreeing well with the values by the Gordon-Taylor equation, confirming the homogeneous random distribution of LA and CL monomers in the synthesized PLCL. The synthesized PLCL and sc-PLA were eventually blended for the fabrication of biodegradable SMPS. The PLCL/sc-PLA blend samples possessed the sc-PLA crystallinity of ∼13%, which effectively worked as crosslinkings, exhibiting shape-memory behavior with various switching temperatures (30.5°C–62 °C) and shape-recovery ratios realized by adjusting the CL ratio of the PLCL copolymers: a lower CL ratio resulted in a higher switching temperature and a higher shape-recovery ratio.
AB - We synthesized new biodegradable shape-memory polymers (SMPs) by blending synthesized poly(D,L-lactide-co-ε-caprolactone) (PLCL) and stereocomplex polylactide (sc-PLA) to be used as biomaterials for medical devices. PLCL copolymers (Mn ∼80,000) with various monomer ratios (LA:CL) were synthesized by the bulk ring-opening polymerization. The glass transition temperature of the resulting PLCL copolymers could be well controlled from −3 °C to 60 °C, agreeing well with the values by the Gordon-Taylor equation, confirming the homogeneous random distribution of LA and CL monomers in the synthesized PLCL. The synthesized PLCL and sc-PLA were eventually blended for the fabrication of biodegradable SMPS. The PLCL/sc-PLA blend samples possessed the sc-PLA crystallinity of ∼13%, which effectively worked as crosslinkings, exhibiting shape-memory behavior with various switching temperatures (30.5°C–62 °C) and shape-recovery ratios realized by adjusting the CL ratio of the PLCL copolymers: a lower CL ratio resulted in a higher switching temperature and a higher shape-recovery ratio.
KW - Biodegradability
KW - Copolymers
KW - Glass transition temperature
KW - Poly(ε-caprolactone)
KW - Polylactide
KW - Shape memory
KW - Shape recovery temperature
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U2 - 10.1016/j.polymer.2021.124190
DO - 10.1016/j.polymer.2021.124190
M3 - Article
AN - SCOPUS:85116027664
VL - 233
JO - Polymer (United Kingdom)
JF - Polymer (United Kingdom)
SN - 0032-3861
M1 - 124190
ER -