Convergent Synthesis of Digalactosyl Diacylglycerols

Shinsuke Inuki, Junichiro Kishi, Emi Kashiwabara, Toshihiko Aiba, Yukari Fujimoto

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Efficient convergent chemical syntheses of digalactosyl diacylglycerols (DGDGs), which have both a galactose-galactose α(1→6)-linkage and a galactose-glycerol β-linkage along with a diacylglycerol containing various kinds of fatty acids, have been accomplished. In order to achieve a concise synthesis, we chose to use allylic protective groups as permanent protective groups. We have also achieved α- and β-selective glycosylations for the respective linkages with high yields as the key steps.

Original languageEnglish
Pages (from-to)6482-6485
Number of pages4
JournalOrganic Letters
Volume19
Issue number24
DOIs
Publication statusPublished - 2017 Dec 15

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galactose
Diglycerides
Galactose
linkages
synthesis
Glycosylation
fatty acids
glycerols
Glycerol
Fatty Acids

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

Cite this

Convergent Synthesis of Digalactosyl Diacylglycerols. / Inuki, Shinsuke; Kishi, Junichiro; Kashiwabara, Emi; Aiba, Toshihiko; Fujimoto, Yukari.

In: Organic Letters, Vol. 19, No. 24, 15.12.2017, p. 6482-6485.

Research output: Contribution to journalArticle

Inuki, S, Kishi, J, Kashiwabara, E, Aiba, T & Fujimoto, Y 2017, 'Convergent Synthesis of Digalactosyl Diacylglycerols', Organic Letters, vol. 19, no. 24, pp. 6482-6485. https://doi.org/10.1021/acs.orglett.7b03043
Inuki, Shinsuke ; Kishi, Junichiro ; Kashiwabara, Emi ; Aiba, Toshihiko ; Fujimoto, Yukari. / Convergent Synthesis of Digalactosyl Diacylglycerols. In: Organic Letters. 2017 ; Vol. 19, No. 24. pp. 6482-6485.
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