Conversion of Bacillus subtilis 168: Natto producing Bacillus subtilis with mosaic genomes

Mitsuhiro Itaya, Kuniko Matsui

Research output: Contribution to journalArticle

18 Citations (Scopus)


Sequential replacement of sequences in the Bacillus subtilis 168 genome with DNA from Bacillus subtilis (natto) conferred the trait of the ability to ferment soybeans to B. subtilis 168 as its genome became mosaic. All mosaic strains retained competence, an intrinsic polygenic trait of the recipient B. subtilis 168.

Original languageEnglish
Pages (from-to)2034-2037
Number of pages4
JournalBioscience, Biotechnology and Biochemistry
Issue number11
Publication statusPublished - 1999 Nov
Externally publishedYes



  • Bacillus subtilis
  • Bacillus subtilis (natto)
  • Horizontal transfer
  • Mosaic genome
  • Transformation

ASJC Scopus subject areas

  • Food Science
  • Biochemistry, Genetics and Molecular Biology(all)
  • Biochemistry
  • Biotechnology
  • Chemistry (miscellaneous)
  • Applied Microbiology and Biotechnology

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