Correlation between insulin-like growth factor-I and obesity index during inpatient treatment in anorexia nervosa in childhood and adolescence

Myong Soon Choe, Akihiro Sato, Hisako Watanabe, Tomonobu Hasegawa

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We studied whether insulin-like growth factor-I (IGF-I) is attributable to nutrition during inpatient treatment in anorexia nervosa (AN) in childhood and adolescence. Nineteen Japanese females with AN, aged 12-19, were enrolled in this study. They were admitted to our hospital during 1993~2003 and treated by the "Keio Method". They had complete bed rest during the first 2 mo of treatment. We studied a possible correlation between serum IGF-I level and obesity index (OI) by using the Spearman rank correlation test. The serum IGF-I level (SDS) and OI (%) was significantly positively correlated on admission (p=.009), at 1 mo (p=.0227), and 2 mo (p=.0063) after admission. These results indicate that the serum IGF-I level is determined by nutritional status in AN in childhood and adolescence under complete bed rest. Copyright

Original languageEnglish
Pages (from-to)21-23
Number of pages3
JournalClinical Pediatric Endocrinology
Issue numberSUPPL. 24
Publication statusPublished - 2005



  • Anorexia nervosa
  • Complete bed rest
  • Insulin-like growth factor-I
  • Obesity index

ASJC Scopus subject areas

  • Endocrinology
  • Pediatrics, Perinatology, and Child Health

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