Corrigendum: Identification of an alternative glycyrrhizin metabolite causing liquorice-induced pseudohyperaldosteronism and the development of ELISA system to detect the predictive biomarker (Front. Pharmacol., (2021), 12, 688508, 10.3389/fphar.2021.688508)

Kan’ichiro Ishiuchi, Osamu Morinaga, Tetsuhiro Yoshino, Miaki Mitamura, Asuka Hirasawa, Yasuhito Maki, Yuuna Tashita, Tsubasa Kondo, Kakuyou Ogawa, Fangyi Lian, Keiko Ogawa-Ochiai, Kiyoshi Minamizawa, Takao Namiki, Masaru Mimura, Kenji Watanabe, Toshiaki Makino

Research output: Contribution to journalComment/debatepeer-review

Abstract

In the published article, there was an error. The numbers of the concentrations were mistaken. A correction has been made to Results, Pharmacokinetics of GA metabolites in female and male EHBRs orally treated with GA, Paragraph 7. These sentences previously stated: “The concentrations of GA and its metabolites 12 h after oral administration of GA in female EHBRs were 3.2 μM of GA, 0.1 μM of 3MGA, 14 μM of 1, 4.3 μM of 2, 6.6 μM of 3, and 166 μM of 4.” and “The concentrations of GA and its metabolites 12 h after oral administration of GA in male EHBRs were 2.6 μM of GA, 1.2 μM of 3MGA, 102 μM of 1, 4.1 μM of 2, 1.2 μM of 3, and 198 μM of 4.” The corrected sentences appear below: “The concentrations of GA and its metabolites 12 h after oral administration of GA in female EHBRs were 2.7 μMof GA, 0.1 μM of 3MGA, 32 μM of 1, 10 μM of 2, 2.0 μMof 3, and 208 μMof 4.” and “The concentrations of GA and its metabolites 12 h after oral administration of GA in male EHBRs were 2.6 μM of GA, 1.6 μM of 3MGA, 177 μM of 1, 8.2 μM of 2, 2.2 μM of 3, and 237 μM of 4.” The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.

Original languageEnglish
Article number1090327
JournalFrontiers in Pharmacology
Volume13
DOIs
Publication statusPublished - 2022 Nov 24

Keywords

  • glycyrrhizin
  • kampo medicine
  • liquorice
  • pseudoaldosteronism
  • sex differences
  • side effect

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)

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