Critical Roles of Myc-ODC Axis in the Cellular Transformation Induced by Myeloproliferative Neoplasm-Associated JAK2 V617F Mutant

Chemical Compounds

• Ornithine 82%
• Ornithine Decarboxylase Inhibitor 62%
• Oncogenic 45%
• Proliferative 43%
• Chemical Transformation 40%
• Growth Factor 38%
• Apoptotic 37%
• Polyamine 35%
• Cell Death 34%
• Mutation 27%
• Biosynthesis 27%
• Protein 13%

Agriculture & Biology

• non-specific protein-tyrosine kinase 100%
• ornithine decarboxylase 78%
• neoplasms 49%
• mutants 38%
• cell proliferation 19%
• growth factors 13%
• apoptosis 13%
• polyamines 7%
• cells 6%
• cell death 6%
• therapeutics 5%
• protein synthesis 5%
• screening 5%
• mutation 4%
• biosynthesis 4%
• gene expression 4%
• mice 4%
• enzymes 3%
• genes 2%

Medicine & Life Sciences

• Janus Kinase 2 91%
• Ornithine Decarboxylase 83%
• Eflornithine 31%
• Neoplasms 21%
• Glycogen Synthase Kinase 3 19%
• Cell Proliferation 14%
• Intercellular Signaling Peptides and Proteins 11%
• Ornithine Decarboxylase Inhibitors 11%
• Proto-Oncogene Proteins c-myc 10%
• myc Genes 8%
• Apoptosis 8%
• Polyamines 8%
• Nude Mice 6%
• Cell Death 5%
• Gene Expression 4%
• Messenger RNA 4%
• Mutation 4%
• Survival 4%
• Enzymes 3%
• Therapeutics 1%