Crosstalk in the measurement of focal brain activation by near-infrared topography

N. Okui, E. Okada

    Research output: Contribution to journalConference article

    Abstract

    Crosstalk between oxy- and deoxy-haemoglobin observed in near-infrared topography is investigated. The light propagation in an adult head model is predicted by Monte Carlo simulation to obtain the change in intensity detected with source-detector pairs on the scalp caused by a focal absorption change in the brain. The topographic images of changes in oxy- and deoxy-haemoglobin are obtained from the changes in intensity detected with source-detector pairs on the scalp. The crosstalk depends on the relative position of the focal absorption change to source-detector pairs. The crosstalk is minimised when the focal absorption change is located below a measurement point that is the midpoint between a source and a detector. Appropriate selection of wavelength pair is effective to reduce the crosstalk in the topographic image.

    Original languageEnglish
    Article number58591A
    Pages (from-to)1-8
    Number of pages8
    JournalProgress in Biomedical Optics and Imaging - Proceedings of SPIE
    Volume5859
    Publication statusPublished - 2005 Dec 19
    EventPhoton Migration and Diffuse-Light Imaging II - Munich, Germany
    Duration: 2005 Jun 122005 Jun 16

    Keywords

    • Crosstalk
    • Monte Carlo simulation
    • Near-infrared topography
    • Optical path length

    ASJC Scopus subject areas

    • Electronic, Optical and Magnetic Materials
    • Biomaterials
    • Atomic and Molecular Physics, and Optics
    • Radiology Nuclear Medicine and imaging

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