Abstract
Crosstalk between oxy- and deoxy-haemoglobin observed in near-infrared topography is investigated. The light propagation in an adult head model is predicted by Monte Carlo simulation to obtain the change in intensity detected with source-detector pairs on the scalp caused by a focal absorption change in the brain. The topographic images of changes in oxy- and deoxy-haemoglobin are obtained from the changes in intensity detected with source-detector pairs on the scalp. The crosstalk depends on the relative position of the focal absorption change to source-detector pairs. The crosstalk is minimised when the focal absorption change is located below a measurement point that is the midpoint between a source and a detector. Appropriate selection of wavelength pair is effective to reduce the crosstalk in the topographic image.
| Original language | English |
|---|---|
| Article number | 58591A |
| Pages (from-to) | 1-8 |
| Number of pages | 8 |
| Journal | Progress in Biomedical Optics and Imaging - Proceedings of SPIE |
| Volume | 5859 |
| Publication status | Published - 2005 Dec 19 |
| Event | Photon Migration and Diffuse-Light Imaging II - Munich, Germany Duration: 2005 Jun 12 → 2005 Jun 16 |
Keywords
- Crosstalk
- Monte Carlo simulation
- Near-infrared topography
- Optical path length
ASJC Scopus subject areas
- Electronic, Optical and Magnetic Materials
- Biomaterials
- Atomic and Molecular Physics, and Optics
- Radiology Nuclear Medicine and imaging