Crystal structure of (±)-(7RS,8SR)-7-methyl-1,4-dioxaspiro[4.5]decane-7,8-diol

Takeshi Oishi, Hiroaki Yamamoto, Tomoya Sugai, Keisuke Fukaya, Yu Yamaguchi, Ami Watanabe, Takaaki Satou, Noritaka Chida

Research output: Contribution to journalArticle

Abstract

In the title compound, C9H16O4, the five-membered dioxolane ring adopts a twist conformation; two adjacent C atoms deviate alternately from the mean plane of other atoms by -0.297(4) and 0.288(4)Å. The spiro-fused cyclohexane ring shows a chair form. The hydroxy group substituted in an axial position makes an intramolecular O - H⋯O hydrogen bond with one of the O atoms in the cyclic ether, forming an S(6) ring motif. In the crystal, the O - H⋯O hydrogen bond involving the equatorial hydroxy group connects the molecules into a zigzag chain with a C(5) motif running along the c axis.

Original languageEnglish
Pages (from-to)1181-1184
Number of pages4
JournalActa Crystallographica Section E: Crystallographic Communications
Volume71
DOIs
Publication statusPublished - 2015

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Crystal structure
Atoms
crystal structure
rings
Hydrogen bonds
Cyclic Ethers
hydrogen bonds
atoms
Cyclohexane
cyclohexane
seats
Conformations
Ethers
ethers
Crystals
Molecules
crystals
decane
molecules
formal glycol

Keywords

  • crystal structure
  • cyclohexane
  • hydrogen bonds
  • hydroxy groups
  • paclitaxel

ASJC Scopus subject areas

  • Condensed Matter Physics
  • Materials Science(all)
  • Chemistry(all)

Cite this

Crystal structure of (±)-(7RS,8SR)-7-methyl-1,4-dioxaspiro[4.5]decane-7,8-diol. / Oishi, Takeshi; Yamamoto, Hiroaki; Sugai, Tomoya; Fukaya, Keisuke; Yamaguchi, Yu; Watanabe, Ami; Satou, Takaaki; Chida, Noritaka.

In: Acta Crystallographica Section E: Crystallographic Communications, Vol. 71, 2015, p. 1181-1184.

Research output: Contribution to journalArticle

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abstract = "In the title compound, C9H16O4, the five-membered dioxolane ring adopts a twist conformation; two adjacent C atoms deviate alternately from the mean plane of other atoms by -0.297(4) and 0.288(4){\AA}. The spiro-fused cyclohexane ring shows a chair form. The hydroxy group substituted in an axial position makes an intramolecular O - H⋯O hydrogen bond with one of the O atoms in the cyclic ether, forming an S(6) ring motif. In the crystal, the O - H⋯O hydrogen bond involving the equatorial hydroxy group connects the molecules into a zigzag chain with a C(5) motif running along the c axis.",
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AU - Oishi, Takeshi

AU - Yamamoto, Hiroaki

AU - Sugai, Tomoya

AU - Fukaya, Keisuke

AU - Yamaguchi, Yu

AU - Watanabe, Ami

AU - Satou, Takaaki

AU - Chida, Noritaka

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AB - In the title compound, C9H16O4, the five-membered dioxolane ring adopts a twist conformation; two adjacent C atoms deviate alternately from the mean plane of other atoms by -0.297(4) and 0.288(4)Å. The spiro-fused cyclohexane ring shows a chair form. The hydroxy group substituted in an axial position makes an intramolecular O - H⋯O hydrogen bond with one of the O atoms in the cyclic ether, forming an S(6) ring motif. In the crystal, the O - H⋯O hydrogen bond involving the equatorial hydroxy group connects the molecules into a zigzag chain with a C(5) motif running along the c axis.

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