Cutaneous T-cell lymphoma with massive co-infiltration of polyclonal B cells

H. Yagi, M. Ogai, T. Izumi, Tamotsu Ebihara, M. Sugiura, Y. Tokura, M. Takigawa

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

A 76-year-old man presented with a 3-month history of a cutaneous nodule on the right thigh. The tumour was composed of CD3+, large atypical cells, and CD20+, small normal-appearing cells. Flow cytometry showed that CD20+ cells outnumbered CD3+ cells. By Southern blot hybridization analyses, the malignant cells were shown to be of T-cell origin, because of the presence of rearranged bands for the β chain of the T-cell receptor, but not for the immunoglobulin heavy chain. This case represents a T-cell lymphoma intermingled with a large number of non-neoplastic B cells.

Original languageEnglish
Pages (from-to)226-230
Number of pages5
JournalBritish Journal of Dermatology
Volume130
Issue number2
DOIs
Publication statusPublished - 1994
Externally publishedYes

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Cutaneous T-Cell Lymphoma
B-Lymphocytes
Immunoglobulin Heavy Chains
T-Cell Lymphoma
T-Cell Antigen Receptor
Southern Blotting
Thigh
Flow Cytometry
T-Lymphocytes
Skin
Neoplasms

ASJC Scopus subject areas

  • Dermatology

Cite this

Yagi, H., Ogai, M., Izumi, T., Ebihara, T., Sugiura, M., Tokura, Y., & Takigawa, M. (1994). Cutaneous T-cell lymphoma with massive co-infiltration of polyclonal B cells. British Journal of Dermatology, 130(2), 226-230. https://doi.org/10.1111/j.1365-2133.1994.tb02905.x

Cutaneous T-cell lymphoma with massive co-infiltration of polyclonal B cells. / Yagi, H.; Ogai, M.; Izumi, T.; Ebihara, Tamotsu; Sugiura, M.; Tokura, Y.; Takigawa, M.

In: British Journal of Dermatology, Vol. 130, No. 2, 1994, p. 226-230.

Research output: Contribution to journalArticle

Yagi, H, Ogai, M, Izumi, T, Ebihara, T, Sugiura, M, Tokura, Y & Takigawa, M 1994, 'Cutaneous T-cell lymphoma with massive co-infiltration of polyclonal B cells', British Journal of Dermatology, vol. 130, no. 2, pp. 226-230. https://doi.org/10.1111/j.1365-2133.1994.tb02905.x
Yagi, H. ; Ogai, M. ; Izumi, T. ; Ebihara, Tamotsu ; Sugiura, M. ; Tokura, Y. ; Takigawa, M. / Cutaneous T-cell lymphoma with massive co-infiltration of polyclonal B cells. In: British Journal of Dermatology. 1994 ; Vol. 130, No. 2. pp. 226-230.
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