Cutaneous T‐cell lymphoma with massive co‐infiltration of polyclonal B cells

H. YAGI, M. OGAI, T. IZUMI, T. EBIHARA, M. SUGIURA, Y. TOKURA, M. TAKIGAWA

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Abstract

Summary A 76‐year‐old man presented with a 3‐month history of a cutaneous nodute on the right thigh. The tumour was composed of CD3+, large atypical cells, and CD20+, small normal‐appearing cells. Flow cytometry showed that CD20+ cells outnumbered CD3+ cells. By Southern blot hybridization analyses, the malignant cells were shown to be of T‐cell origin, because of the presence of rearranged bands for the β chain of the T‐cell receptor, but not for the immunoglobulin heavy chain. This case represents a T‐cell lymphoma intermingled with a large number of non‐neoplastic B cells.

Original languageEnglish
Pages (from-to)226-230
Number of pages5
JournalBritish Journal of Dermatology
Volume130
Issue number2
DOIs
Publication statusPublished - 1994 Feb

ASJC Scopus subject areas

  • Dermatology

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    YAGI, H., OGAI, M., IZUMI, T., EBIHARA, T., SUGIURA, M., TOKURA, Y., & TAKIGAWA, M. (1994). Cutaneous T‐cell lymphoma with massive co‐infiltration of polyclonal B cells. British Journal of Dermatology, 130(2), 226-230. https://doi.org/10.1111/j.1365-2133.1994.tb02905.x