Cytologic evaluation of conjunctival epithelium after cataract surgery

Kazuo Tsubota, M. Yamada, K. Kajiwara, S. Ugajin, T. Hasegawa, T. K. Kobayashi

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Although numerous studies have examined corneal epithelial wound healing, few reports describe conjunctival wound healing. Thus, we evaluated the conjunctival epithelium by brush cytology, in which a miniature brush was used to collect many cells relatively noninvasively. The temporal and superior conjunctivae were examined before and after cataract extraction on the first, third, seventh, and fourteenth days and then the first, second, and third months postoperatively, in a group of 20 patients (9 men and 11 women with a mean age of 69 years 3 months ± 10 years). The cells collected were stained by the Papanicolau method. Each postoperative specimen contained keratinized, polygonal, round, columnar, elongated, and inflammatory cells, as well as cells with nuclear alterations. No keratinized, elongated, or inflammatory cells were observed preoperatively. In contrast, columnar cells, which were present preoperatively, decreased during the wound healing process. Such nuclear changes as chromatin formation or the appearance of snake-like figures were observed in several patients postoperatively. These cellular changes may represent altered differentiation during the healing process. However, the conjunctival epithelium returned to normal within 2 months postoperatively in all patients.

Original languageEnglish
Pages (from-to)418-426
Number of pages9
JournalCornea
Volume11
Issue number5
Publication statusPublished - 1992
Externally publishedYes

Fingerprint

Cataract
Epithelium
Wound Healing
Cataract Extraction
Snakes
Conjunctiva
Chromatin
Cell Biology

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Tsubota, K., Yamada, M., Kajiwara, K., Ugajin, S., Hasegawa, T., & Kobayashi, T. K. (1992). Cytologic evaluation of conjunctival epithelium after cataract surgery. Cornea, 11(5), 418-426.

Cytologic evaluation of conjunctival epithelium after cataract surgery. / Tsubota, Kazuo; Yamada, M.; Kajiwara, K.; Ugajin, S.; Hasegawa, T.; Kobayashi, T. K.

In: Cornea, Vol. 11, No. 5, 1992, p. 418-426.

Research output: Contribution to journalArticle

Tsubota, K, Yamada, M, Kajiwara, K, Ugajin, S, Hasegawa, T & Kobayashi, TK 1992, 'Cytologic evaluation of conjunctival epithelium after cataract surgery', Cornea, vol. 11, no. 5, pp. 418-426.
Tsubota K, Yamada M, Kajiwara K, Ugajin S, Hasegawa T, Kobayashi TK. Cytologic evaluation of conjunctival epithelium after cataract surgery. Cornea. 1992;11(5):418-426.
Tsubota, Kazuo ; Yamada, M. ; Kajiwara, K. ; Ugajin, S. ; Hasegawa, T. ; Kobayashi, T. K. / Cytologic evaluation of conjunctival epithelium after cataract surgery. In: Cornea. 1992 ; Vol. 11, No. 5. pp. 418-426.
@article{cae64fa2046942718782a9d28969ce1a,
title = "Cytologic evaluation of conjunctival epithelium after cataract surgery",
abstract = "Although numerous studies have examined corneal epithelial wound healing, few reports describe conjunctival wound healing. Thus, we evaluated the conjunctival epithelium by brush cytology, in which a miniature brush was used to collect many cells relatively noninvasively. The temporal and superior conjunctivae were examined before and after cataract extraction on the first, third, seventh, and fourteenth days and then the first, second, and third months postoperatively, in a group of 20 patients (9 men and 11 women with a mean age of 69 years 3 months ± 10 years). The cells collected were stained by the Papanicolau method. Each postoperative specimen contained keratinized, polygonal, round, columnar, elongated, and inflammatory cells, as well as cells with nuclear alterations. No keratinized, elongated, or inflammatory cells were observed preoperatively. In contrast, columnar cells, which were present preoperatively, decreased during the wound healing process. Such nuclear changes as chromatin formation or the appearance of snake-like figures were observed in several patients postoperatively. These cellular changes may represent altered differentiation during the healing process. However, the conjunctival epithelium returned to normal within 2 months postoperatively in all patients.",
author = "Kazuo Tsubota and M. Yamada and K. Kajiwara and S. Ugajin and T. Hasegawa and Kobayashi, {T. K.}",
year = "1992",
language = "English",
volume = "11",
pages = "418--426",
journal = "Cornea",
issn = "0277-3740",
publisher = "Lippincott Williams and Wilkins",
number = "5",

}

TY - JOUR

T1 - Cytologic evaluation of conjunctival epithelium after cataract surgery

AU - Tsubota, Kazuo

AU - Yamada, M.

AU - Kajiwara, K.

AU - Ugajin, S.

AU - Hasegawa, T.

AU - Kobayashi, T. K.

PY - 1992

Y1 - 1992

N2 - Although numerous studies have examined corneal epithelial wound healing, few reports describe conjunctival wound healing. Thus, we evaluated the conjunctival epithelium by brush cytology, in which a miniature brush was used to collect many cells relatively noninvasively. The temporal and superior conjunctivae were examined before and after cataract extraction on the first, third, seventh, and fourteenth days and then the first, second, and third months postoperatively, in a group of 20 patients (9 men and 11 women with a mean age of 69 years 3 months ± 10 years). The cells collected were stained by the Papanicolau method. Each postoperative specimen contained keratinized, polygonal, round, columnar, elongated, and inflammatory cells, as well as cells with nuclear alterations. No keratinized, elongated, or inflammatory cells were observed preoperatively. In contrast, columnar cells, which were present preoperatively, decreased during the wound healing process. Such nuclear changes as chromatin formation or the appearance of snake-like figures were observed in several patients postoperatively. These cellular changes may represent altered differentiation during the healing process. However, the conjunctival epithelium returned to normal within 2 months postoperatively in all patients.

AB - Although numerous studies have examined corneal epithelial wound healing, few reports describe conjunctival wound healing. Thus, we evaluated the conjunctival epithelium by brush cytology, in which a miniature brush was used to collect many cells relatively noninvasively. The temporal and superior conjunctivae were examined before and after cataract extraction on the first, third, seventh, and fourteenth days and then the first, second, and third months postoperatively, in a group of 20 patients (9 men and 11 women with a mean age of 69 years 3 months ± 10 years). The cells collected were stained by the Papanicolau method. Each postoperative specimen contained keratinized, polygonal, round, columnar, elongated, and inflammatory cells, as well as cells with nuclear alterations. No keratinized, elongated, or inflammatory cells were observed preoperatively. In contrast, columnar cells, which were present preoperatively, decreased during the wound healing process. Such nuclear changes as chromatin formation or the appearance of snake-like figures were observed in several patients postoperatively. These cellular changes may represent altered differentiation during the healing process. However, the conjunctival epithelium returned to normal within 2 months postoperatively in all patients.

UR - http://www.scopus.com/inward/record.url?scp=0026782871&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0026782871&partnerID=8YFLogxK

M3 - Article

VL - 11

SP - 418

EP - 426

JO - Cornea

JF - Cornea

SN - 0277-3740

IS - 5

ER -