TY - JOUR
T1 - Cytomegalovirus enteritis in immunocompetent subjects
T2 - A case report and review of the literature
AU - Karigane, Daiki
AU - Takaya, Saho
AU - Seki, Yuki
AU - Mastumoto, Yuka
AU - Onose, Akira
AU - Kosakai, Arifumi
AU - Sugaya, Norio
AU - Mori, Takehiko
PY - 2014/5
Y1 - 2014/5
N2 - Cytomegalovirus (CMV) enteritis (or colitis) is generally diagnosed in immunocompromised patients in association with human immunodeficiency virus infection as well as in recipients of solid organ or hematopoietic stem cell transplant. CMV enteritis has been reported only sporadically in immunocompetent individuals. We encountered a 76-year-old woman who developed CMV enteritis without any previously identified immunocompromised states. An extensive literature review of 33 cases of CMV enteritis or colitis diagnosed in immunocompetent individuals, including the present case, revealed that the median age of the patients was 68, the accompanying symptoms were diarrhea (76%), abdominal pain (52%), and hematochezia or melena (27%), and that the outcome was generally favorable, including resolution without any treatment in 24% of the patients. CMV enteritis should be recognized more widely as a disease entity not only in immunocompromised patients but also in immunocompetent individuals, especially in elderly populations.
AB - Cytomegalovirus (CMV) enteritis (or colitis) is generally diagnosed in immunocompromised patients in association with human immunodeficiency virus infection as well as in recipients of solid organ or hematopoietic stem cell transplant. CMV enteritis has been reported only sporadically in immunocompetent individuals. We encountered a 76-year-old woman who developed CMV enteritis without any previously identified immunocompromised states. An extensive literature review of 33 cases of CMV enteritis or colitis diagnosed in immunocompetent individuals, including the present case, revealed that the median age of the patients was 68, the accompanying symptoms were diarrhea (76%), abdominal pain (52%), and hematochezia or melena (27%), and that the outcome was generally favorable, including resolution without any treatment in 24% of the patients. CMV enteritis should be recognized more widely as a disease entity not only in immunocompromised patients but also in immunocompetent individuals, especially in elderly populations.
KW - Colitis
KW - Cytomegalovirus
KW - Enteritis
KW - Ganciclovir
KW - Immunocompetent individuals
UR - http://www.scopus.com/inward/record.url?scp=84903585421&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84903585421&partnerID=8YFLogxK
U2 - 10.1016/j.jiac.2013.12.004
DO - 10.1016/j.jiac.2013.12.004
M3 - Article
C2 - 24751234
AN - SCOPUS:84903585421
SN - 1341-321X
VL - 20
SP - 325
EP - 329
JO - Journal of Infection and Chemotherapy
JF - Journal of Infection and Chemotherapy
IS - 5
ER -
