Cytomegalovirus enteritis in immunocompetent subjects: A case report and review of the literature

Daiki Karigane, Saho Takaya, Yuki Seki, Yuka Mastumoto, Akira Onose, Arifumi Kosakai, Norio Sugaya, Takehiko Mori

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Cytomegalovirus (CMV) enteritis (or colitis) is generally diagnosed in immunocompromised patients in association with human immunodeficiency virus infection as well as in recipients of solid organ or hematopoietic stem cell transplant. CMV enteritis has been reported only sporadically in immunocompetent individuals. We encountered a 76-year-old woman who developed CMV enteritis without any previously identified immunocompromised states. An extensive literature review of 33 cases of CMV enteritis or colitis diagnosed in immunocompetent individuals, including the present case, revealed that the median age of the patients was 68, the accompanying symptoms were diarrhea (76%), abdominal pain (52%), and hematochezia or melena (27%), and that the outcome was generally favorable, including resolution without any treatment in 24% of the patients. CMV enteritis should be recognized more widely as a disease entity not only in immunocompromised patients but also in immunocompetent individuals, especially in elderly populations.

Original languageEnglish
Pages (from-to)325-329
Number of pages5
JournalJournal of Infection and Chemotherapy
Volume20
Issue number5
DOIs
Publication statusPublished - 2014 May

Keywords

  • Colitis
  • Cytomegalovirus
  • Enteritis
  • Ganciclovir
  • Immunocompetent individuals

ASJC Scopus subject areas

  • Microbiology (medical)
  • Pharmacology (medical)
  • Infectious Diseases

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