Dacryoadenitis associated with Acanthamoeba keratitis

Machiko Tomita, Shigeto Shimmura, Kazuo Tsubota, Jun Shimazaki

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Objective: To report the incidence of dacryoadenitis as a symptom associated with Acanthamoeba keratitis. Methods: We investigated all cases of Acanthamoeba keratitis (20 patients and 21 eyes) diagnosed and treated at Tokyo Dental College, Ichikawa General Hospital, Ichikawa, Japan, between May 1, 1994, and November 30, 2005. We recorded the incidence of dacryoadenitis diagnosed using clinical signs of lacrimal gland swelling and pain on pressure, computed tomography, magnetic resonance imaging, and histopathologic analysis. Results: Eight eyes (38%) of 8 patients had dacryoadenitis simultaneously with Acanthamoeba keratitis. Dacryoadenitis was diagnosed using histopathologic analysis and computed tomography in 1 patient, histopathologic analysis and magnetic resonance imaging in 1, magnetic resonance imaging in 2, and clinical signs alone in 4. Histopathologic examination in 2 patients revealed moderate infiltration of lymphocytes and plasma cells in the lacrimal gland compatible with dacryoadenitis. No Acanthamoeba organisms were found in the lacrimal gland. The standard protocol for Acanthamoeba keratitis was performed without particular treatment of dacryoadenitis in all patients. Lacrimal gland swelling improved after a mean of 10 weeks (range, 4-17 weeks) in conjunction with symptoms of keratitis; however, 1 patient (patient 1) required levator muscle surgery and blepharoplasty for residual ptosis. Conclusion: Dacryoadenitis is a clinical finding associated with Acanthamoeba keratitis.

Original languageEnglish
Pages (from-to)1239-1242
Number of pages4
JournalArchives of Ophthalmology
Volume124
Issue number9
DOIs
Publication statusPublished - 2006

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Acanthamoeba Keratitis
Dacryocystitis
Lacrimal Apparatus
Magnetic Resonance Imaging
Tomography
Blepharoplasty
Acanthamoeba
Tokyo
Keratitis
Incidence
Plasma Cells
General Hospitals
Tooth
Japan
Lymphocytes
Pressure
Pain
Muscles

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Dacryoadenitis associated with Acanthamoeba keratitis. / Tomita, Machiko; Shimmura, Shigeto; Tsubota, Kazuo; Shimazaki, Jun.

In: Archives of Ophthalmology, Vol. 124, No. 9, 2006, p. 1239-1242.

Research output: Contribution to journalArticle

Tomita, Machiko ; Shimmura, Shigeto ; Tsubota, Kazuo ; Shimazaki, Jun. / Dacryoadenitis associated with Acanthamoeba keratitis. In: Archives of Ophthalmology. 2006 ; Vol. 124, No. 9. pp. 1239-1242.
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