Dedifferentiated parosteal osteosarcoma with well-differentiated metastases

Katsuhito Takeuchi, Takeshi Morii, Hiroo Yabe, Hideo Morioka, Makio Mukai, Yoshiaki Toyama

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Metastases of dedifferentiated sarcoma usually contain a dedifferentiated component. We report a rare case of dedifferentiated parosteal osteosarcoma (dd-POS) with well-differentiated multiple metastases in a 65-year-old woman with a painful firm mass on her thigh. Radiological examination revealed that the mass arose from the surface of her femur without medullary involvement. Multiple intramuscular metastases were detected in her lower leg on MR imaging. Small subcutaneous palpable masses were identified on her left lower leg, buttock, chest wall and head. An open biopsy and above-the-knee amputation were performed, and the mass on her femur was diagnosed as a dd-POS. However, histological examination on the subcutaneous lesions in her lower leg, buttock and head showed low-grade conventional POS without dedifferentiated components. To the best of our knowledge, this is the first report of a dd-POS with multiple metastases that do not contain any dedifferentiated components.

Original languageEnglish
Pages (from-to)778-782
Number of pages5
JournalSkeletal Radiology
Volume35
Issue number10
DOIs
Publication statusPublished - 2006 Oct

Fingerprint

Osteosarcoma
Neoplasm Metastasis
Leg
Buttocks
Femur
Head
Thoracic Wall
Thigh
Amputation
Sarcoma
Knee
Biopsy

Keywords

  • Dedifferentiated parosteal osteosarcoma
  • Femur
  • MRI
  • Well-differentiated metastasis

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Takeuchi, K., Morii, T., Yabe, H., Morioka, H., Mukai, M., & Toyama, Y. (2006). Dedifferentiated parosteal osteosarcoma with well-differentiated metastases. Skeletal Radiology, 35(10), 778-782. https://doi.org/10.1007/s00256-005-0066-0

Dedifferentiated parosteal osteosarcoma with well-differentiated metastases. / Takeuchi, Katsuhito; Morii, Takeshi; Yabe, Hiroo; Morioka, Hideo; Mukai, Makio; Toyama, Yoshiaki.

In: Skeletal Radiology, Vol. 35, No. 10, 10.2006, p. 778-782.

Research output: Contribution to journalArticle

Takeuchi, K, Morii, T, Yabe, H, Morioka, H, Mukai, M & Toyama, Y 2006, 'Dedifferentiated parosteal osteosarcoma with well-differentiated metastases', Skeletal Radiology, vol. 35, no. 10, pp. 778-782. https://doi.org/10.1007/s00256-005-0066-0
Takeuchi, Katsuhito ; Morii, Takeshi ; Yabe, Hiroo ; Morioka, Hideo ; Mukai, Makio ; Toyama, Yoshiaki. / Dedifferentiated parosteal osteosarcoma with well-differentiated metastases. In: Skeletal Radiology. 2006 ; Vol. 35, No. 10. pp. 778-782.
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