Abstract
In recent years, many anthocyanin-containing dietary supplements of various dosages and formulations have been sold through advertising their large number of beneficial effects. On the other hand, there is an increased risk of distributing deteriorated supplements to consumers due to lax regulations, because in Japan these supplements are classified as food. Spectrophotometric methods are commonly used to control the quality of supplements. However, these methods have limitations with regard to assessing deterioration. In this study, we evaluated a new index for detection of deteriorated products. The stability of 3 formulations and the quality of 20 supplements were investigated by ultra-high performance liquid chromatography, which is superior to spectrophotometry for identifying and quantifying individual anthocyanins. The stability was not only affected by storage temperature but also by formulation. We defined "Degradation Index" (DI) as an indicator of the deterioration of supplements. Of 20 supplements investigated, the DI of 5 supplements was more than 3-fold the value of Bilberon-25, and the worst one was 12.7-fold. These results suggest that DI could be a useful quality control index for detecting deteriorated supplements.
| Original language | English |
|---|---|
| Journal | Journal of Food Science |
| Volume | 78 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - 2013 Mar |
| Externally published | Yes |
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Keywords
- Bilberry anthocyanins
- Degradation Index
- Quality
- Storage
- UHPLC
ASJC Scopus subject areas
- Food Science
Cite this
Degradation Index for Quality Evaluation of Commercial Dietary Supplements of Bilberry Extract. / Yamamoto, Masao; Yamaura, Katsunori; Ishiwatari, Makiko; Shimada, Maki; Kado, Sayaka; Seki, Hiroko; Shimada, Norimoto; Ueno, Koichi.
In: Journal of Food Science, Vol. 78, No. 3, 03.2013.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Degradation Index for Quality Evaluation of Commercial Dietary Supplements of Bilberry Extract
AU - Yamamoto, Masao
AU - Yamaura, Katsunori
AU - Ishiwatari, Makiko
AU - Shimada, Maki
AU - Kado, Sayaka
AU - Seki, Hiroko
AU - Shimada, Norimoto
AU - Ueno, Koichi
PY - 2013/3
Y1 - 2013/3
N2 - In recent years, many anthocyanin-containing dietary supplements of various dosages and formulations have been sold through advertising their large number of beneficial effects. On the other hand, there is an increased risk of distributing deteriorated supplements to consumers due to lax regulations, because in Japan these supplements are classified as food. Spectrophotometric methods are commonly used to control the quality of supplements. However, these methods have limitations with regard to assessing deterioration. In this study, we evaluated a new index for detection of deteriorated products. The stability of 3 formulations and the quality of 20 supplements were investigated by ultra-high performance liquid chromatography, which is superior to spectrophotometry for identifying and quantifying individual anthocyanins. The stability was not only affected by storage temperature but also by formulation. We defined "Degradation Index" (DI) as an indicator of the deterioration of supplements. Of 20 supplements investigated, the DI of 5 supplements was more than 3-fold the value of Bilberon-25, and the worst one was 12.7-fold. These results suggest that DI could be a useful quality control index for detecting deteriorated supplements.
AB - In recent years, many anthocyanin-containing dietary supplements of various dosages and formulations have been sold through advertising their large number of beneficial effects. On the other hand, there is an increased risk of distributing deteriorated supplements to consumers due to lax regulations, because in Japan these supplements are classified as food. Spectrophotometric methods are commonly used to control the quality of supplements. However, these methods have limitations with regard to assessing deterioration. In this study, we evaluated a new index for detection of deteriorated products. The stability of 3 formulations and the quality of 20 supplements were investigated by ultra-high performance liquid chromatography, which is superior to spectrophotometry for identifying and quantifying individual anthocyanins. The stability was not only affected by storage temperature but also by formulation. We defined "Degradation Index" (DI) as an indicator of the deterioration of supplements. Of 20 supplements investigated, the DI of 5 supplements was more than 3-fold the value of Bilberon-25, and the worst one was 12.7-fold. These results suggest that DI could be a useful quality control index for detecting deteriorated supplements.
KW - Bilberry anthocyanins
KW - Degradation Index
KW - Quality
KW - Storage
KW - UHPLC
UR - http://www.scopus.com/inward/record.url?scp=84874581255&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84874581255&partnerID=8YFLogxK
U2 - 10.1111/1750-3841.12043
DO - 10.1111/1750-3841.12043
M3 - Article
C2 - 23458753
AN - SCOPUS:84874581255
VL - 78
JO - Journal of Food Science
JF - Journal of Food Science
SN - 0022-1147
IS - 3
ER -