Design of a new phosphate binder, anion exchange resin, based on microcalorimeter measurements

Hiroyoshi Inoue, Sho Ichi Yamagishi

Research output: Contribution to journalArticle

Abstract

It has been suggested that resin wettability is advantageous for dietary phosphate binding in the gastrointestinal tract. To evaluate the effect of anion exchange resin wetting properties on in vivo phosphate binding ability, four types of ethylene glycol dimethacrylate cross-linking 4-vinylpyridinium anion exchange resins (EGDMA-4VP) were synthesized.

Original languageEnglish
Pages (from-to)250-254
Number of pages5
JournalLetters in Drug Design and Discovery
Volume2
Issue number3
DOIs
Publication statusPublished - 2005 May 1
Externally publishedYes

Keywords

  • Ethylene glycol dimethacrylate cross-linking 4-vinylpyridinium
  • Gastrointestinal content
  • Immersion heat
  • Phosphate binding
  • Sevelamer HCl
  • Wetting

ASJC Scopus subject areas

  • Molecular Medicine
  • Pharmaceutical Science
  • Drug Discovery

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