Design of a new phosphate binder, anion exchange resin, based on microcalorimeter measurements

Hiroyoshi Inoue; Sho Ichi Yamagishi

doi:10.2174/1570180053765138

Design of a new phosphate binder, anion exchange resin, based on microcalorimeter measurements

Research output: Contribution to journal › Article › peer-review

Abstract

It has been suggested that resin wettability is advantageous for dietary phosphate binding in the gastrointestinal tract. To evaluate the effect of anion exchange resin wetting properties on in vivo phosphate binding ability, four types of ethylene glycol dimethacrylate cross-linking 4-vinylpyridinium anion exchange resins (EGDMA-4VP) were synthesized.

Original language	English
Pages (from-to)	250-254
Number of pages	5
Journal	Letters in Drug Design and Discovery
Volume	2
Issue number	3
DOIs	https://doi.org/10.2174/1570180053765138
Publication status	Published - 2005 May 1
Externally published	Yes

Keywords

Ethylene glycol dimethacrylate cross-linking 4-vinylpyridinium
Gastrointestinal content
Immersion heat
Phosphate binding
Sevelamer HCl
Wetting

ASJC Scopus subject areas

Molecular Medicine
Pharmaceutical Science
Drug Discovery

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10.2174/1570180053765138

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abstract = "It has been suggested that resin wettability is advantageous for dietary phosphate binding in the gastrointestinal tract. To evaluate the effect of anion exchange resin wetting properties on in vivo phosphate binding ability, four types of ethylene glycol dimethacrylate cross-linking 4-vinylpyridinium anion exchange resins (EGDMA-4VP) were synthesized.",

keywords = "Ethylene glycol dimethacrylate cross-linking 4-vinylpyridinium, Gastrointestinal content, Immersion heat, Phosphate binding, Sevelamer HCl, Wetting",

author = "Hiroyoshi Inoue and Yamagishi, {Sho Ichi}",

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AU - Yamagishi, Sho Ichi

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N2 - It has been suggested that resin wettability is advantageous for dietary phosphate binding in the gastrointestinal tract. To evaluate the effect of anion exchange resin wetting properties on in vivo phosphate binding ability, four types of ethylene glycol dimethacrylate cross-linking 4-vinylpyridinium anion exchange resins (EGDMA-4VP) were synthesized.

AB - It has been suggested that resin wettability is advantageous for dietary phosphate binding in the gastrointestinal tract. To evaluate the effect of anion exchange resin wetting properties on in vivo phosphate binding ability, four types of ethylene glycol dimethacrylate cross-linking 4-vinylpyridinium anion exchange resins (EGDMA-4VP) were synthesized.

KW - Ethylene glycol dimethacrylate cross-linking 4-vinylpyridinium

KW - Gastrointestinal content

KW - Immersion heat

KW - Phosphate binding

KW - Sevelamer HCl

KW - Wetting

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ER -

Design of a new phosphate binder, anion exchange resin, based on microcalorimeter measurements

Abstract

Keywords

ASJC Scopus subject areas

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