Design of periodic control systems for circadian rhythm of mammals

Tetsuya Kusumi, Hiromitsu Ohmori

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Recently, developing molecular biology and system biology, the mechanism of the circadian rhythm in which the inside of the body rhythm of the living thing is ruled is being clarified at the cell level. On the other hand, it is said that various sicknesses are related in the medicine and pharmacology to the disorder of the circadian rhythm. Therefore, it is thought that to restore an altered rhythm is a goal of these therapies. In this paper, we study the 10-states circadian model of Drosophila and propose a close-loop control based on flatness-based adaptive control to achieve circadian rhythm restoration.

Original languageEnglish
Title of host publicationProceedings of SICE Annual Conference 2008 - International Conference on Instrumentation, Control and Information Technology
Pages1400-1404
Number of pages5
DOIs
Publication statusPublished - 2008 Dec 1
EventSICE Annual Conference 2008 - International Conference on Instrumentation, Control and Information Technology - Tokyo, Japan
Duration: 2008 Aug 202008 Aug 22

Publication series

NameProceedings of the SICE Annual Conference

Other

OtherSICE Annual Conference 2008 - International Conference on Instrumentation, Control and Information Technology
CountryJapan
CityTokyo
Period08/8/2008/8/22

Keywords

  • Adaptive control
  • Circadian rhythm
  • Flatness-based control
  • Synchronization control
  • System biology

ASJC Scopus subject areas

  • Control and Systems Engineering
  • Computer Science Applications
  • Electrical and Electronic Engineering

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  • Cite this

    Kusumi, T., & Ohmori, H. (2008). Design of periodic control systems for circadian rhythm of mammals. In Proceedings of SICE Annual Conference 2008 - International Conference on Instrumentation, Control and Information Technology (pp. 1400-1404). [4654877] (Proceedings of the SICE Annual Conference). https://doi.org/10.1109/SICE.2008.4654877