Design of two complementary copolymers that work as a glue for cell-laden collagen gels

Taihei Nishimoto; Ko Matsukawa; Kenichi Nagase; Hideko Kanazawa; Aya Mizutani Akimoto; Ryo Yoshida

doi:10.1039/d0cc03689g

Design of two complementary copolymers that work as a glue for cell-laden collagen gels

Taihei Nishimoto, Ko Matsukawa, Kenichi Nagase, Hideko Kanazawa, Aya Mizutani Akimoto, Ryo Yoshida

School of Pharmaceutical Sciences

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

We designed two types of copolymers that play a role of "polymeric glue". They introduced surface adhesive functions to cell-laden collagen gels. The present study realised surface functionalisation of naturally derived hydrogels and suggested a novel method for manipulating living cells. This method is potentially useful for in vitro reconstruction of 3D living tissue since it enabled versatile and cytocompatible hydrogel surface modification by a simple procedure without any special equipment.

Original language	English
Pages (from-to)	10545-10548
Number of pages	4
Journal	Chemical Communications
Volume	56
Issue number	72
DOIs	https://doi.org/10.1039/d0cc03689g
Publication status	Published - 2020 Sept 16

ASJC Scopus subject areas

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
Chemistry(all)
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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abstract = "We designed two types of copolymers that play a role of {"}polymeric glue{"}. They introduced surface adhesive functions to cell-laden collagen gels. The present study realised surface functionalisation of naturally derived hydrogels and suggested a novel method for manipulating living cells. This method is potentially useful for in vitro reconstruction of 3D living tissue since it enabled versatile and cytocompatible hydrogel surface modification by a simple procedure without any special equipment. ",

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AU - Matsukawa, Ko

AU - Nagase, Kenichi

AU - Kanazawa, Hideko

AU - Akimoto, Aya Mizutani

AU - Yoshida, Ryo

N1 - Funding Information: This work was partly financially supported through a SEN-TAN grant (JPMJSN16B3) from the Japan Science and Technology Agency (JST) (to A. M. A.). Publisher Copyright: © 2020 The Royal Society of Chemistry.

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Design of two complementary copolymers that work as a glue for cell-laden collagen gels

Abstract

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