Design strategy for a near-infrared fluorescence probe for matrix metalloproteinase utilizing highly cell permeable boron dipyrromethene

Medicine & Life Sciences

• dipyrromethene 100%
• Boron 72%
• Matrix Metalloproteinases 48%
• Fluorescence 41%
• 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene 18%
• Energy Transfer 14%
• Matrix Metalloproteinase 14 7%
• Fluorescent Dyes 5%
• Fluorescence Microscopy 5%
• Tumor Biomarkers 5%
• Heterografts 5%
• Extracellular Matrix 4%
• Peptide Hydrolases 4%
• Atherosclerosis 4%
• Peptides 3%
• Inflammation 3%
• Injections 3%
• Neoplasms 1%

Engineering & Materials Science

• Metalloproteases 95%
• Fluorescence 57%
• Boron 56%
• Infrared radiation 43%
• Forster resonance energy transfer 15%
• Heterografts 9%
• Tissue 8%
• Tumor Biomarkers 8%
• Peptide Hydrolases 7%
• Fluorescence microscopy 7%
• Peptides 6%
• Dyes 5%
• Transparency 5%
• Tumors 5%
• Chemical activation 4%
• Wavelength 4%
• Imaging techniques 3%
• Substrates 3%

Chemical Compounds

• Boron Atom 43%
• Probe 30%
• Fluorescence 28%
• Fluorescence Resonance Energy Transfer 9%
• Tumor Marker 6%
• Fluorescent Dye 5%
• Fluorescence Microscopy 5%
• Transparency 5%
• Marker 4%
• Wavelength 3%
• Donor 3%
• Diffusion 3%