Design, synthesis and evaluation of a boronic acid based artificial receptor for l-DOPA in aqueous media

Haruna Ueno, Takayuki Iwata, Nozomi Koshiba, Daisuke Takahashi, Kazunobu Toshima

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Design and synthesis of a boronic acid based artificial receptor which selectively and effectively bound to a neurotransmitter, l-DOPA (1), in aqueous media. In addition, the synthetic receptor was found to effectively inhibit the DDC (l-DOPA decarboxylase) enzymatic reaction under physiological conditions.

Original languageEnglish
Pages (from-to)10403-10405
Number of pages3
JournalChemical Communications
Volume49
Issue number88
DOIs
Publication statusPublished - 2013 Nov 14

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Artificial Receptors
Boronic Acids
Carboxy-Lyases
Acids
Neurotransmitter Agents

ASJC Scopus subject areas

  • Metals and Alloys
  • Materials Chemistry
  • Surfaces, Coatings and Films
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Catalysis
  • Chemistry(all)

Cite this

Design, synthesis and evaluation of a boronic acid based artificial receptor for l-DOPA in aqueous media. / Ueno, Haruna; Iwata, Takayuki; Koshiba, Nozomi; Takahashi, Daisuke; Toshima, Kazunobu.

In: Chemical Communications, Vol. 49, No. 88, 14.11.2013, p. 10403-10405.

Research output: Contribution to journalArticle

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