Design, synthesis and evaluation of a boronic acid based artificial receptor for 1-dopa in aqueous media

Haruna Ueno; Takayuki Iwata; Nozomi Koshiba; Daisuke Takahashi; Kazunobu Toshima

doi:10.1039/c3cc45275a

Design, synthesis and evaluation of a boronic acid based artificial receptor for 1-dopa in aqueous media

Haruna Ueno, Takayuki Iwata, Nozomi Koshiba, Daisuke Takahashi, Kazunobu Toshima

Department of Applied Chemistry

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

Abstract

Design and synthesis of a boronic acid based artificial receptor which selectively and effectively bound to a neurotransmitter, 1-DOPA (1), in aqueous media. In addition, the synthetic receptor was found to effectively inhibit the DDC (1-DOPA decarboxylase) enzymatic reaction under physiological conditions.

Original language	English
Pages (from-to)	10403-10405
Number of pages	3
Journal	Chemical Communications
Volume	49
Issue number	88
DOIs	https://doi.org/10.1039/c3cc45275a
Publication status	Published - 2013 Oct 10

ASJC Scopus subject areas

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
Chemistry(all)
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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abstract = "Design and synthesis of a boronic acid based artificial receptor which selectively and effectively bound to a neurotransmitter, 1-DOPA (1), in aqueous media. In addition, the synthetic receptor was found to effectively inhibit the DDC (1-DOPA decarboxylase) enzymatic reaction under physiological conditions.",

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AU - Koshiba, Nozomi

AU - Takahashi, Daisuke

AU - Toshima, Kazunobu

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Design, synthesis and evaluation of a boronic acid based artificial receptor for 1-dopa in aqueous media

Abstract

ASJC Scopus subject areas

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