Detection of a coronary artery vessel wall: Performance of 0.3 mm fine-cell detector computed tomography - A phantom study

Minoru Yamada, Masahiro Jinzaki, Yutaka Tanami, Kazuhiro Matsumoto, Akihisa Ueno, Masatake Nukui, Yasuhiro Imai, Yotaro Ishihara, Akihiko Nishide, Kosuke Sasaki, Sachio Kuribayashi

Research output: Contribution to journalArticlepeer-review

12 Citations (Scopus)

Abstract

The purpose of this study was to evaluate whether experimental fine-cell detector computed tomography with a 0.3125 mm cell (0.3 mm cell CT) can improve the detection of coronary vessel walls compared with conventional 64-slice computed tomography with a 0.625 mm cell (0.6 mm cell CT). A coronary vessel wall phantom was scanned using 0.6 mm cell CT and 0.3 mm cell CT. The data for 0.3 mm cell CT were obtained using four protocols: a radiation dose equal, double, triple or quadruple that were used in the 0.6 mm cell CT protocol. The detectable size of the vessel wall was assessed based on the first and second derivative functions, and the minimum measurable values were compared using a paired t-test. As a result, the minimum detectable wall thickness of 0.6 mm cell CT (1.5 mm) was significantly larger than that of 0.3 mm cell CT performed using the triple- and quadruple-dose protocols (0.9 mm) and the double-dose protocol (1.1 mm). The difference in the minimum detectable vessel wall thickness measured using 0.6 mm cell CT (1.5 0.1 mm) and 0.3 mm cell CT (0.9 0.1 mm, 1.1 0.2 mm) was significant (p < 0.01). We concluded that 0.3 mm cell CT improved the detection of coronary vessel walls when a more than double-dose protocol was used compared with 0.6 mm cell CT.

Original languageEnglish
Pages (from-to)5235-5247
Number of pages13
JournalPhysics in Medicine and Biology
Volume56
Issue number16
DOIs
Publication statusPublished - 2011 Aug 21

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging

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