TY - JOUR
T1 - Detection of perineural tumor invasion of the head and neck
T2 - Clinical use of thallium-201 SPECT/CT image fusion
AU - Nakahara, Tadaki
AU - Suzuki, Takayuki
AU - Kunieda, Etsuo
AU - Momoshima, Suketaka
AU - Shigematsu, Naoyuki
AU - Kubo, Atsushi
PY - 2008/8
Y1 - 2008/8
N2 - A patient with adenoid cystic carcinoma of the skull base was treated with radiotherapy because of perineural tumor invasion (PTI). Treatment evaluation using magnetic resonance (MR) imaging showed disease progression of PTI outside the irradiated area, whereas it was difficult to evaluate the therapeutic effect of radiotherapy because the irradiated lesions still had contrast enhancement. Thallium-201 SPECT/CT image fusion was performed to evaluate tumor extent and viability after therapy. During the follow-up period, disease progression was noted in the areas of abnormal uptake on the thallium-201 SPECT/CT fusion images, but the lesions with no uptake remained unchanged on follow-up MR imaging. Thallium-201 SPECT/CT image fusion can be used for precise localization of viable PTI in head and neck cancer patients who had been previously treated.
AB - A patient with adenoid cystic carcinoma of the skull base was treated with radiotherapy because of perineural tumor invasion (PTI). Treatment evaluation using magnetic resonance (MR) imaging showed disease progression of PTI outside the irradiated area, whereas it was difficult to evaluate the therapeutic effect of radiotherapy because the irradiated lesions still had contrast enhancement. Thallium-201 SPECT/CT image fusion was performed to evaluate tumor extent and viability after therapy. During the follow-up period, disease progression was noted in the areas of abnormal uptake on the thallium-201 SPECT/CT fusion images, but the lesions with no uptake remained unchanged on follow-up MR imaging. Thallium-201 SPECT/CT image fusion can be used for precise localization of viable PTI in head and neck cancer patients who had been previously treated.
KW - Adenoid cystic carcinoma
KW - Perineural tumor invasion
KW - Radiotherapy
KW - SPECT/CT
KW - Thallium-201
UR - http://www.scopus.com/inward/record.url?scp=51249086111&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=51249086111&partnerID=8YFLogxK
U2 - 10.1097/RLU.0b013e31817dea6b
DO - 10.1097/RLU.0b013e31817dea6b
M3 - Article
C2 - 18645382
AN - SCOPUS:51249086111
SN - 0363-9762
VL - 33
SP - 567
EP - 570
JO - Clinical Nuclear Medicine
JF - Clinical Nuclear Medicine
IS - 8
ER -