Determination of medetomidine, atipamezole and midazolam in pig plasma by liquid chromatography‐mass spectrometry

Hideko Kanazawa, Ryohei Nishimura, Nobuo Sasaki, Akira Takeuchi, Nobuharu Takai, Yoshiko Nagata, Yoshikazu Matsushima

Research output: Contribution to journalArticlepeer-review

26 Citations (Scopus)

Abstract

Medetomidine, atipamezole and midazolam in pig plasma were determined by liquid chromatography‐mass spectrometry (LCMS) with an atmospheric pressure chemical ionization interface system by the use of detomidine as an internal standard. The method was applied to studies of pharmacokinetic behaviour of these drugs.

Original languageEnglish
Pages (from-to)188-191
Number of pages4
JournalBiomedical Chromatography
Volume9
Issue number4
DOIs
Publication statusPublished - 1995 Jan 1

ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry
  • Molecular Biology
  • Pharmacology
  • Drug Discovery
  • Clinical Biochemistry

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