Development and validation of asthma questionnaire for assessing and achieving best control in preschool-age children

Kazuki Sato, Yasunori Sato, Mizuho Nagao, Naoki Shimojo, Shigemi Yoshihara, Yuichi Adachi, Makoto Kameda, Akihiko Terada, Takao Fujisawa

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Background: Several patient-/caregiver-completed questionnaires have been utilized for the assessment of asthma control. However, due to the diversity in medical/social circumstances, they may not be optimal for use in all countries. The Japanese pediatric asthma guideline (JPGL) aims at higher levels of control compared with other international guidelines, based on a strong social demand for best care. We developed a new control test to help meet that demand. Methods: A 34-item working questionnaire was developed based on input from pediatric asthma specialists and the caregivers of preschool children with asthma. The questionnaire was administered to caregivers of 565 patients aged <6 years who had physician-diagnosed asthma or β2-agonist-responsive recurrent wheeze. Then, 6 questions for assessing JPGL-defined control levels were selected from the 34 questions by stepwise logistic regression methods using randomly selected questionnaires completed by two-thirds of the caregivers. We named that set of questions the Best Asthma Control Test for Preschoolers (Best ACT-P). Validation of Best ACT-P was performed using the remaining completed questionnaires. Results: The 6 questions asked about the frequency/severity of cold-induced wheeze, nighttime awakening, exercise-induced symptoms, and disruption of family life due to asthma in the past 4 weeks and hospitalization in the past 12 months. The 6-item logistic model showed good statistical fit, and the scores for the physicians' ratings of the asthma control differed significantly in the hypothetical direction. Conclusions: Best ACT-P is a valid caregiver-completed questionnaire of asthma control in preschoolers in whom total control needs to be achieved.

Original languageEnglish
Pages (from-to)307-312
Number of pages6
JournalPediatric Allergy and Immunology
Volume27
Issue number3
DOIs
Publication statusPublished - 2016 May 1
Externally publishedYes

Fingerprint

Preschool Children
Asthma
Caregivers
Guidelines
Pediatrics
Surveys and Questionnaires
Logistic Models
Physicians
Hospitalization
Exercise

Keywords

  • Asthma
  • Caregiver-completed questionnaire
  • Control
  • Control test
  • Preschool children

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Immunology and Allergy
  • Immunology

Cite this

Development and validation of asthma questionnaire for assessing and achieving best control in preschool-age children. / Sato, Kazuki; Sato, Yasunori; Nagao, Mizuho; Shimojo, Naoki; Yoshihara, Shigemi; Adachi, Yuichi; Kameda, Makoto; Terada, Akihiko; Fujisawa, Takao.

In: Pediatric Allergy and Immunology, Vol. 27, No. 3, 01.05.2016, p. 307-312.

Research output: Contribution to journalArticle

Sato, K, Sato, Y, Nagao, M, Shimojo, N, Yoshihara, S, Adachi, Y, Kameda, M, Terada, A & Fujisawa, T 2016, 'Development and validation of asthma questionnaire for assessing and achieving best control in preschool-age children', Pediatric Allergy and Immunology, vol. 27, no. 3, pp. 307-312. https://doi.org/10.1111/pai.12523
Sato, Kazuki ; Sato, Yasunori ; Nagao, Mizuho ; Shimojo, Naoki ; Yoshihara, Shigemi ; Adachi, Yuichi ; Kameda, Makoto ; Terada, Akihiko ; Fujisawa, Takao. / Development and validation of asthma questionnaire for assessing and achieving best control in preschool-age children. In: Pediatric Allergy and Immunology. 2016 ; Vol. 27, No. 3. pp. 307-312.
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