Development of a compact artificial gill using concentrated hemoglobin solution as the oxygen carrier

Kenichi Nagase, Fukashi Kohori, Kiyotaka Sakai

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

An artificial gill was developed using a concentrated hemoglobin solution containing inositol hexaphosphate (IHP), as the oxygen carrier solution, with the oxygen affinity controlled by temperature. Oxygen dissolved in sea water is first taken up from water to the oxygen carrier solution at 293K. The oxygen carrier solution is then heated and the oxygen is released from the oxygen carrier solution to expired air at 310K. The enhancement factors of the oxygen carrier solution that indicate its performance were obtained from the oxygen uptake rate and oxygen release rate. The values were approximately 3 at oxygen uptake and 16 at oxygen release. The scale-up for a human being at rest was estimated using these values, and the optimal operating condition was determined. The required membrane surface area for a human being is 63.8m2. The oxygen partial pressure of inspiration is 20.7kPa, adequate for the respiration. These indicate the feasibility of a compact and portable artificial gill device.

Original languageEnglish
Pages (from-to)281-292
Number of pages12
JournalJournal of Membrane Science
Volume215
Issue number1-2
DOIs
Publication statusPublished - 2003 Apr 15
Externally publishedYes

Fingerprint

Hemoglobin
hemoglobin
Hemoglobins
Oxygen
oxygen
expired air
inositols
Phytic Acid
inspiration
Water
sea water
Partial Pressure
Dissolved oxygen
respiration
Seawater
Partial pressure
partial pressure
affinity
Respiration
Air

Keywords

  • Facilitated transport
  • Fiber membranes
  • Gas separation modules
  • Oxygen transfer

ASJC Scopus subject areas

  • Filtration and Separation
  • Polymers and Plastics

Cite this

Development of a compact artificial gill using concentrated hemoglobin solution as the oxygen carrier. / Nagase, Kenichi; Kohori, Fukashi; Sakai, Kiyotaka.

In: Journal of Membrane Science, Vol. 215, No. 1-2, 15.04.2003, p. 281-292.

Research output: Contribution to journalArticle

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