Development of a reversible fluorescent probe for reactive sulfur species, sulfane sulfur, and its biological application

Yoko Takano, Kenjiro Hanaoka, Kazuhito Shimamoto, Ryo Miyamoto, Toru Komatsu, Tasuku Ueno, Takuya Terai, Hideo Kimura, Tetsuo Nagano, Yasuteru Urano

Research output: Contribution to journalArticlepeer-review

50 Citations (Scopus)

Abstract

We report a reversible off/on fluorescent probe for monitoring concentration changes of sulfane sulfur by utilizing the unique ability of sulfane sulfur to bind reversibly to other sulfur atoms and the intramolecular spirocyclization reaction of xanthene dyes. It reversibly visualized sulfane sulfur in living A549 cells and primary-cultured hippocampal astrocytes.

Original languageEnglish
Pages (from-to)1064-1067
Number of pages4
JournalChemical Communications
Volume53
Issue number6
DOIs
Publication statusPublished - 2017
Externally publishedYes

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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