Development of a Vaccinia H1-Related (VHR) Phosphatase Inhibitor with a Nonacidic Phosphate-Mimicking Core Structure

Go Hirai, Ayako Tsuchiya, Yusuke Koyama, Yuko Otani, Kana Oonuma, Kosuke Dodo, Siro Simizu, Hiroyuki Osada, Mikiko Sodeoka

Research output: Contribution to journalArticle

16 Citations (Scopus)
Original languageEnglish
Pages (from-to)617-622
Number of pages6
JournalChemMedChem
Volume6
Issue number4
DOIs
Publication statusPublished - 2011 Apr 4
Externally publishedYes

Fingerprint

Dual-Specificity Phosphatases
Cultured Tumor Cells
Molecular Mimicry
Vaccinia
NIH 3T3 Cells
Vaccinia virus
Enzyme Inhibitors
Structure-Activity Relationship
Biological Products
Phosphoric Monoester Hydrolases
Inhibitory Concentration 50
Cell Cycle
Animals
Phosphates
Enzymes

Keywords

  • Cell cycle
  • Dual-specificity protein phosphatases
  • Enzymes
  • Inhibitors
  • Natural product analogues

ASJC Scopus subject areas

  • Pharmacology, Toxicology and Pharmaceutics(all)
  • Organic Chemistry
  • Molecular Medicine

Cite this

Hirai, G., Tsuchiya, A., Koyama, Y., Otani, Y., Oonuma, K., Dodo, K., ... Sodeoka, M. (2011). Development of a Vaccinia H1-Related (VHR) Phosphatase Inhibitor with a Nonacidic Phosphate-Mimicking Core Structure. ChemMedChem, 6(4), 617-622. https://doi.org/10.1002/cmdc.201100107

Development of a Vaccinia H1-Related (VHR) Phosphatase Inhibitor with a Nonacidic Phosphate-Mimicking Core Structure. / Hirai, Go; Tsuchiya, Ayako; Koyama, Yusuke; Otani, Yuko; Oonuma, Kana; Dodo, Kosuke; Simizu, Siro; Osada, Hiroyuki; Sodeoka, Mikiko.

In: ChemMedChem, Vol. 6, No. 4, 04.04.2011, p. 617-622.

Research output: Contribution to journalArticle

Hirai, G, Tsuchiya, A, Koyama, Y, Otani, Y, Oonuma, K, Dodo, K, Simizu, S, Osada, H & Sodeoka, M 2011, 'Development of a Vaccinia H1-Related (VHR) Phosphatase Inhibitor with a Nonacidic Phosphate-Mimicking Core Structure', ChemMedChem, vol. 6, no. 4, pp. 617-622. https://doi.org/10.1002/cmdc.201100107
Hirai, Go ; Tsuchiya, Ayako ; Koyama, Yusuke ; Otani, Yuko ; Oonuma, Kana ; Dodo, Kosuke ; Simizu, Siro ; Osada, Hiroyuki ; Sodeoka, Mikiko. / Development of a Vaccinia H1-Related (VHR) Phosphatase Inhibitor with a Nonacidic Phosphate-Mimicking Core Structure. In: ChemMedChem. 2011 ; Vol. 6, No. 4. pp. 617-622.
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