Development of extended-nano femtolitter mess-pipette in living single cell analysis device

Tatsuro Nakao, Yutaka Kazoe, Kyojiro Morikawa, Ling Lin, Ayumi Yoshizaki, Kazuma Mawatari, Takehiko Kitamori

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Here we report a development of fL (10-15 L) mess-pipette (volumetric pipette) utilizing precise fabrication of 100-nm structure on fused silica and hydrophobic Laplace valve. During verification of fL volumetric pipette, we discovered that drying of sample is the key issue on fL liquid handling in gas phase. By quick application of pressure (~ms), we minimized the effect of drying and 11 fL of water was successfully isolated and transported without loss. This study will greatly contribute to analytical chemistry by providing a novel method of volumetry and manipulation of fL liquid.

Original languageEnglish
Title of host publication21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017
PublisherChemical and Biological Microsystems Society
Pages930-931
Number of pages2
ISBN (Electronic)9780692941836
Publication statusPublished - 2020 Jan 1
Externally publishedYes
Event21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017 - Savannah, United States
Duration: 2017 Oct 222017 Oct 26

Publication series

Name21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017

Conference

Conference21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017
CountryUnited States
CitySavannah
Period17/10/2217/10/26

Keywords

  • Extended-Nano Space
  • Femto Litter
  • Pipette
  • Single Cell

ASJC Scopus subject areas

  • Chemical Engineering (miscellaneous)
  • Bioengineering

Fingerprint Dive into the research topics of 'Development of extended-nano femtolitter mess-pipette in living single cell analysis device'. Together they form a unique fingerprint.

  • Cite this

    Nakao, T., Kazoe, Y., Morikawa, K., Lin, L., Yoshizaki, A., Mawatari, K., & Kitamori, T. (2020). Development of extended-nano femtolitter mess-pipette in living single cell analysis device. In 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017 (pp. 930-931). (21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017). Chemical and Biological Microsystems Society.