Abstract
In the medical field, blood viscosity is known to be correlated with several diseases such as cardiac infarction and brain infarction. The blood viscosity may contribute to detection of diseases at an early stage and may give an indication of health state. There are several methods for measuring blood viscosity such as rotational viscometers and falling ball viscometers, but they need several milliliter sample volume and take several tens of seconds or several minutes to measure. So, we have developed a new viscometer which can measure viscosity within 1 ms and with micro-liter sample volume. In the present study, we have developed a new viscometer by the laser-induced capillary wave using YAG laser. In this paper, first, we have measured viscosities of Newtonian liquids with 90 μl sample volume and showed good agreement within ± 10% from the reference values in the range from 10-1 to 10 1 mPa·s. Then, we have measured healthy human blood with 90 μl sample volume and compared to the reference values. The measured results of blood viscosity and surface tension were 4.5 mPamiddot; and 54 mN/m, respectively. The results were in good agreement with the reference with the estimated shear rate by the present method in the range of 102 to 103 s-1.
| Original language | English |
|---|---|
| Pages (from-to) | 1290-1296 |
| Number of pages | 7 |
| Journal | Nihon Kikai Gakkai Ronbunshu, B Hen/Transactions of the Japan Society of Mechanical Engineers, Part B |
| Volume | 76 |
| Issue number | 768 |
| Publication status | Published - 2010 Aug |
| Externally published | Yes |
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Keywords
- Blood viscosity
- Laser-Induced capillary wave
- Measurement technique
- Surface tension
- Thermophysical properties
ASJC Scopus subject areas
- Mechanical Engineering
- Condensed Matter Physics
Cite this
Development of high-speed sensing technique for blood viscosity with micro-liter sample volume. / Muramoto, Yuichi; Takahashi, Naohiro; Kamata, Naoko; Nagasaka, Yuji.
In: Nihon Kikai Gakkai Ronbunshu, B Hen/Transactions of the Japan Society of Mechanical Engineers, Part B, Vol. 76, No. 768, 08.2010, p. 1290-1296.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Development of high-speed sensing technique for blood viscosity with micro-liter sample volume
AU - Muramoto, Yuichi
AU - Takahashi, Naohiro
AU - Kamata, Naoko
AU - Nagasaka, Yuji
PY - 2010/8
Y1 - 2010/8
N2 - In the medical field, blood viscosity is known to be correlated with several diseases such as cardiac infarction and brain infarction. The blood viscosity may contribute to detection of diseases at an early stage and may give an indication of health state. There are several methods for measuring blood viscosity such as rotational viscometers and falling ball viscometers, but they need several milliliter sample volume and take several tens of seconds or several minutes to measure. So, we have developed a new viscometer which can measure viscosity within 1 ms and with micro-liter sample volume. In the present study, we have developed a new viscometer by the laser-induced capillary wave using YAG laser. In this paper, first, we have measured viscosities of Newtonian liquids with 90 μl sample volume and showed good agreement within ± 10% from the reference values in the range from 10-1 to 10 1 mPa·s. Then, we have measured healthy human blood with 90 μl sample volume and compared to the reference values. The measured results of blood viscosity and surface tension were 4.5 mPamiddot; and 54 mN/m, respectively. The results were in good agreement with the reference with the estimated shear rate by the present method in the range of 102 to 103 s-1.
AB - In the medical field, blood viscosity is known to be correlated with several diseases such as cardiac infarction and brain infarction. The blood viscosity may contribute to detection of diseases at an early stage and may give an indication of health state. There are several methods for measuring blood viscosity such as rotational viscometers and falling ball viscometers, but they need several milliliter sample volume and take several tens of seconds or several minutes to measure. So, we have developed a new viscometer which can measure viscosity within 1 ms and with micro-liter sample volume. In the present study, we have developed a new viscometer by the laser-induced capillary wave using YAG laser. In this paper, first, we have measured viscosities of Newtonian liquids with 90 μl sample volume and showed good agreement within ± 10% from the reference values in the range from 10-1 to 10 1 mPa·s. Then, we have measured healthy human blood with 90 μl sample volume and compared to the reference values. The measured results of blood viscosity and surface tension were 4.5 mPamiddot; and 54 mN/m, respectively. The results were in good agreement with the reference with the estimated shear rate by the present method in the range of 102 to 103 s-1.
KW - Blood viscosity
KW - Laser-Induced capillary wave
KW - Measurement technique
KW - Surface tension
KW - Thermophysical properties
UR - http://www.scopus.com/inward/record.url?scp=78349237463&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=78349237463&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:78349237463
VL - 76
SP - 1290
EP - 1296
JO - Nihon Kikai Gakkai Ronbunshu, B Hen/Transactions of the Japan Society of Mechanical Engineers, Part B
JF - Nihon Kikai Gakkai Ronbunshu, B Hen/Transactions of the Japan Society of Mechanical Engineers, Part B
SN - 0387-5016
IS - 768
ER -