Development of high yield plasma separation device from whole blood preventing blood cell clogging in a micro/extended-nano chip

Jumpei Mitsuse, Kyojiro Morikawa, Emi Mori, Ryoichi Ohta, Yutaka Kazoe, Kazuma Mawatari, Takehiko Kitamori

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We fabricated the device for high yield plasma separation without clogging of blood cells. To control plasma flow after filtering blood cells, dense blood cell flow, and support flow for dilution of dense blood cells, a filter using size-regulated and closely packed extended-nano channels (10-1000 nm) on a micro wall and a capillary which worked as drain and back-pressure regulator were successfully integrated in the device. This device will be useful for blood analysis using a micro/extended-nano chip.

Original languageEnglish
Title of host publication21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017
PublisherChemical and Biological Microsystems Society
Pages1483-1484
Number of pages2
ISBN (Electronic)9780692941836
Publication statusPublished - 2020
Externally publishedYes
Event21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017 - Savannah, United States
Duration: 2017 Oct 222017 Oct 26

Publication series

Name21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017

Conference

Conference21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017
Country/TerritoryUnited States
CitySavannah
Period17/10/2217/10/26

Keywords

  • Blood analysis
  • Extended-nano space
  • Microfluidics
  • Plasma separation

ASJC Scopus subject areas

  • Chemical Engineering (miscellaneous)
  • Bioengineering

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