Diagnostic performance of ultrasound without any colon preparation for detecting colorectal polyps in pediatric patients

Takahiro Hosokawa, Mayumi Hosokawa, Yutaka Tanami, Yumiko Sato, Ryosuke Nambu, Itaru Iwama, Eiji Oguma, Yoshitake Yamada

Research output: Contribution to journalArticle

Abstract

Background: There are limited data on the sensitivity, specificity and accuracy of ultrasound for detecting colorectal polyps in children and young adults. Objective: To evaluate the diagnostic accuracy of ultrasound, without any colon preparation, for detecting colorectal polyps in pediatric patients and to determine the causes of false-negative results. Materials and methods: We included 74 children with clinical signs like rectal bleeding, abdominal pain or diarrhea who underwent both ultrasound and colonoscopy. We evaluated the diagnostic performance of ultrasound for detecting colorectal polyps before colonoscopy, which served as the reference standard. We used Fisher exact and Student’s t-tests for statistical analyses. Results: Fifteen pediatric patients were diagnosed with colorectal polyps in the transverse (n=3), descending (n=1) and sigmoid (n=6) colon, and rectum (n=5) by colonoscopy. The sensitivity, specificity and accuracy of ultrasound to detect colorectal polyps were 47% (7/15, 95% confidence interval [CI] 21–73%), 100% (59/59, 95% CI 94–100%) and 89% (66/74, 95% CI 80–95%), respectively. The volume (mean ± standard deviation) of polyps not detected by ultrasound was significantly smaller than that detected (270±380 mm3 vs. 4,600±3,900 mm3, P=0.0124). We observed a significant difference in the location between the polyps detected and not detected by ultrasound (rectal/non-rectal=0/7 vs. 5/3, P=0.0256). No significant age or gender difference was observed. Conclusion: The accuracy for detecting colorectal polyps by ultrasound was 89% (95% CI, 80–95%) in our cohort. Polyps found in the rectum and relatively smaller polyps accounted for several false-negative cases.

Original languageEnglish
JournalPediatric Radiology
DOIs
Publication statusPublished - 2019 Jan 1

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Polyps
Ultrasonography
Colon
Pediatrics
Colonoscopy
Confidence Intervals
Rectum
Sensitivity and Specificity
Sigmoid Colon
Abdominal Pain
Young Adult
Diarrhea
Hemorrhage
Students

Keywords

  • Children
  • Colon
  • Colonoscopy
  • Juvenile polyp
  • Screening
  • Sonography
  • Ultrasound

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Radiology Nuclear Medicine and imaging

Cite this

Diagnostic performance of ultrasound without any colon preparation for detecting colorectal polyps in pediatric patients. / Hosokawa, Takahiro; Hosokawa, Mayumi; Tanami, Yutaka; Sato, Yumiko; Nambu, Ryosuke; Iwama, Itaru; Oguma, Eiji; Yamada, Yoshitake.

In: Pediatric Radiology, 01.01.2019.

Research output: Contribution to journalArticle

Hosokawa, Takahiro ; Hosokawa, Mayumi ; Tanami, Yutaka ; Sato, Yumiko ; Nambu, Ryosuke ; Iwama, Itaru ; Oguma, Eiji ; Yamada, Yoshitake. / Diagnostic performance of ultrasound without any colon preparation for detecting colorectal polyps in pediatric patients. In: Pediatric Radiology. 2019.
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abstract = "Background: There are limited data on the sensitivity, specificity and accuracy of ultrasound for detecting colorectal polyps in children and young adults. Objective: To evaluate the diagnostic accuracy of ultrasound, without any colon preparation, for detecting colorectal polyps in pediatric patients and to determine the causes of false-negative results. Materials and methods: We included 74 children with clinical signs like rectal bleeding, abdominal pain or diarrhea who underwent both ultrasound and colonoscopy. We evaluated the diagnostic performance of ultrasound for detecting colorectal polyps before colonoscopy, which served as the reference standard. We used Fisher exact and Student’s t-tests for statistical analyses. Results: Fifteen pediatric patients were diagnosed with colorectal polyps in the transverse (n=3), descending (n=1) and sigmoid (n=6) colon, and rectum (n=5) by colonoscopy. The sensitivity, specificity and accuracy of ultrasound to detect colorectal polyps were 47{\%} (7/15, 95{\%} confidence interval [CI] 21–73{\%}), 100{\%} (59/59, 95{\%} CI 94–100{\%}) and 89{\%} (66/74, 95{\%} CI 80–95{\%}), respectively. The volume (mean ± standard deviation) of polyps not detected by ultrasound was significantly smaller than that detected (270±380 mm3 vs. 4,600±3,900 mm3, P=0.0124). We observed a significant difference in the location between the polyps detected and not detected by ultrasound (rectal/non-rectal=0/7 vs. 5/3, P=0.0256). No significant age or gender difference was observed. Conclusion: The accuracy for detecting colorectal polyps by ultrasound was 89{\%} (95{\%} CI, 80–95{\%}) in our cohort. Polyps found in the rectum and relatively smaller polyps accounted for several false-negative cases.",
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AU - Tanami, Yutaka

AU - Sato, Yumiko

AU - Nambu, Ryosuke

AU - Iwama, Itaru

AU - Oguma, Eiji

AU - Yamada, Yoshitake

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