Diagnostic usefulness of bronchoalveolar lavage in Hermansky-Pudlak syndrome: A case with double lung cancers

Kumi Takahashi, Takashi Ishida, Go Ogura, Taeko Ishii, Kengo Oshima, Suguru Sato, Miho Muroi, Kenya Kanazawa, Junpei Saito., Yoshinori Otsuka, Kazuo Watanabe, Makoto Handa, Mitsuru Munakata

Research output: Contribution to journalArticlepeer-review

7 Citations (Scopus)

Abstract

A 65-year-old man was admitted to our hospital because of dyspnea on exertion. He had oculocutaneous albinism innately and his parents were consanguineous. His chest roentgenogram on admission showed reticulonodular infiltrates and cystic changes throughout both lung fields, and 7 cm mass in the left middle field. Cytology of bronchoalveolar lavage fluid (BALF) revealed macrophages containing ceroid. The diagnosis of HPS was made clinically and the tumor was diagnosed as poorly differentiated adenocarcinoma of the lung. He died of respiratory failure. By autopsy, additional well-differentiated adenocarcinoma was detected. Cytology of BALF was useful to confirm ceroid accumulation in the lung.

Original languageEnglish
Pages (from-to)972-976
Number of pages5
JournalInternal Medicine
Volume43
Issue number10
DOIs
Publication statusPublished - 2004 Oct 1

Keywords

  • Ceroid
  • Interstitial Pneumonia
  • Lung cancer
  • Oculocutaneous albinism

ASJC Scopus subject areas

  • Internal Medicine

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