Diagnostic usefulness of bronchoalveolar lavage in Hermansky-Pudlak syndrome

A case with double lung cancers

Kumi Takahashi, Takashi Ishida, Go Ogura, Taeko Ishii, Kengo Oshima, Suguru Sato, Miho Muroi, Kenya Kanazawa, Junpei Saito., Yoshinori Otsuka, Kazuo Watanabe, Makoto Handa, Mitsuru Munakata

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

A 65-year-old man was admitted to our hospital because of dyspnea on exertion. He had oculocutaneous albinism innately and his parents were consanguineous. His chest roentgenogram on admission showed reticulonodular infiltrates and cystic changes throughout both lung fields, and 7 cm mass in the left middle field. Cytology of bronchoalveolar lavage fluid (BALF) revealed macrophages containing ceroid. The diagnosis of HPS was made clinically and the tumor was diagnosed as poorly differentiated adenocarcinoma of the lung. He died of respiratory failure. By autopsy, additional well-differentiated adenocarcinoma was detected. Cytology of BALF was useful to confirm ceroid accumulation in the lung.

Original languageEnglish
Pages (from-to)972-976
Number of pages5
JournalInternal Medicine
Volume43
Issue number10
DOIs
Publication statusPublished - 2004 Oct

Fingerprint

Hermanski-Pudlak Syndrome
Ceroid
Bronchoalveolar Lavage Fluid
Bronchoalveolar Lavage
Cell Biology
Lung Neoplasms
Oculocutaneous Albinism
Lung
Respiratory Insufficiency
Dyspnea
Autopsy
Adenocarcinoma
Thorax
Parents
Macrophages
Neoplasms

Keywords

  • Ceroid
  • Interstitial Pneumonia
  • Lung cancer
  • Oculocutaneous albinism

ASJC Scopus subject areas

  • Internal Medicine

Cite this

Takahashi, K., Ishida, T., Ogura, G., Ishii, T., Oshima, K., Sato, S., ... Munakata, M. (2004). Diagnostic usefulness of bronchoalveolar lavage in Hermansky-Pudlak syndrome: A case with double lung cancers. Internal Medicine, 43(10), 972-976. https://doi.org/10.2169/internalmedicine.43.972

Diagnostic usefulness of bronchoalveolar lavage in Hermansky-Pudlak syndrome : A case with double lung cancers. / Takahashi, Kumi; Ishida, Takashi; Ogura, Go; Ishii, Taeko; Oshima, Kengo; Sato, Suguru; Muroi, Miho; Kanazawa, Kenya; Saito., Junpei; Otsuka, Yoshinori; Watanabe, Kazuo; Handa, Makoto; Munakata, Mitsuru.

In: Internal Medicine, Vol. 43, No. 10, 10.2004, p. 972-976.

Research output: Contribution to journalArticle

Takahashi, K, Ishida, T, Ogura, G, Ishii, T, Oshima, K, Sato, S, Muroi, M, Kanazawa, K, Saito., J, Otsuka, Y, Watanabe, K, Handa, M & Munakata, M 2004, 'Diagnostic usefulness of bronchoalveolar lavage in Hermansky-Pudlak syndrome: A case with double lung cancers', Internal Medicine, vol. 43, no. 10, pp. 972-976. https://doi.org/10.2169/internalmedicine.43.972
Takahashi, Kumi ; Ishida, Takashi ; Ogura, Go ; Ishii, Taeko ; Oshima, Kengo ; Sato, Suguru ; Muroi, Miho ; Kanazawa, Kenya ; Saito., Junpei ; Otsuka, Yoshinori ; Watanabe, Kazuo ; Handa, Makoto ; Munakata, Mitsuru. / Diagnostic usefulness of bronchoalveolar lavage in Hermansky-Pudlak syndrome : A case with double lung cancers. In: Internal Medicine. 2004 ; Vol. 43, No. 10. pp. 972-976.
@article{957fde68ec8046c991d039b832067c6b,
title = "Diagnostic usefulness of bronchoalveolar lavage in Hermansky-Pudlak syndrome: A case with double lung cancers",
abstract = "A 65-year-old man was admitted to our hospital because of dyspnea on exertion. He had oculocutaneous albinism innately and his parents were consanguineous. His chest roentgenogram on admission showed reticulonodular infiltrates and cystic changes throughout both lung fields, and 7 cm mass in the left middle field. Cytology of bronchoalveolar lavage fluid (BALF) revealed macrophages containing ceroid. The diagnosis of HPS was made clinically and the tumor was diagnosed as poorly differentiated adenocarcinoma of the lung. He died of respiratory failure. By autopsy, additional well-differentiated adenocarcinoma was detected. Cytology of BALF was useful to confirm ceroid accumulation in the lung.",
keywords = "Ceroid, Interstitial Pneumonia, Lung cancer, Oculocutaneous albinism",
author = "Kumi Takahashi and Takashi Ishida and Go Ogura and Taeko Ishii and Kengo Oshima and Suguru Sato and Miho Muroi and Kenya Kanazawa and Junpei Saito. and Yoshinori Otsuka and Kazuo Watanabe and Makoto Handa and Mitsuru Munakata",
year = "2004",
month = "10",
doi = "10.2169/internalmedicine.43.972",
language = "English",
volume = "43",
pages = "972--976",
journal = "Internal Medicine",
issn = "0918-2918",
publisher = "Japanese Society of Internal Medicine",
number = "10",

}

TY - JOUR

T1 - Diagnostic usefulness of bronchoalveolar lavage in Hermansky-Pudlak syndrome

T2 - A case with double lung cancers

AU - Takahashi, Kumi

AU - Ishida, Takashi

AU - Ogura, Go

AU - Ishii, Taeko

AU - Oshima, Kengo

AU - Sato, Suguru

AU - Muroi, Miho

AU - Kanazawa, Kenya

AU - Saito., Junpei

AU - Otsuka, Yoshinori

AU - Watanabe, Kazuo

AU - Handa, Makoto

AU - Munakata, Mitsuru

PY - 2004/10

Y1 - 2004/10

N2 - A 65-year-old man was admitted to our hospital because of dyspnea on exertion. He had oculocutaneous albinism innately and his parents were consanguineous. His chest roentgenogram on admission showed reticulonodular infiltrates and cystic changes throughout both lung fields, and 7 cm mass in the left middle field. Cytology of bronchoalveolar lavage fluid (BALF) revealed macrophages containing ceroid. The diagnosis of HPS was made clinically and the tumor was diagnosed as poorly differentiated adenocarcinoma of the lung. He died of respiratory failure. By autopsy, additional well-differentiated adenocarcinoma was detected. Cytology of BALF was useful to confirm ceroid accumulation in the lung.

AB - A 65-year-old man was admitted to our hospital because of dyspnea on exertion. He had oculocutaneous albinism innately and his parents were consanguineous. His chest roentgenogram on admission showed reticulonodular infiltrates and cystic changes throughout both lung fields, and 7 cm mass in the left middle field. Cytology of bronchoalveolar lavage fluid (BALF) revealed macrophages containing ceroid. The diagnosis of HPS was made clinically and the tumor was diagnosed as poorly differentiated adenocarcinoma of the lung. He died of respiratory failure. By autopsy, additional well-differentiated adenocarcinoma was detected. Cytology of BALF was useful to confirm ceroid accumulation in the lung.

KW - Ceroid

KW - Interstitial Pneumonia

KW - Lung cancer

KW - Oculocutaneous albinism

UR - http://www.scopus.com/inward/record.url?scp=8844222722&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=8844222722&partnerID=8YFLogxK

U2 - 10.2169/internalmedicine.43.972

DO - 10.2169/internalmedicine.43.972

M3 - Article

VL - 43

SP - 972

EP - 976

JO - Internal Medicine

JF - Internal Medicine

SN - 0918-2918

IS - 10

ER -