Different modes of coupling of delta-opioid receptors with GTP-binding proteins in membrane preparations from guinea-pig striatum and leal myenteric plexus

M. Satoh, H. Ueda, H. Misawa, J. Harada, K. Nishimura, T. Katada, M. Ui

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

The [3H][D-Pen2,D-Pen5]enkephalin ([3H]DPDPE) binding was markedly inhibited by GTPγS in both membrane preparations from striatum and ileal myenteric plexus of guinea-pig. DPDPE stimulated low-K(m) GTPase and inhibited adenylate cyclase in the latter preparation, but did not affect the G-protein activities including GDP-GTP exchange in the former one.

Original languageEnglish
Title of host publicationNew leads in opioid research
Subtitle of host publicationproceedings of the International Narcotics Research Conference. ICS914
EditorsJ.M. Van Ree, A.H. Mulder, V.M. Wiegant, T.B. Van Wimersma Greidanus, J.M. Van Ree, A.H. Mulder, V.M. Wiegant, T.B. Van Wimersma Greidanus
PublisherElsevier Science Publishers B.V.
Pages297-298
Number of pages2
ISBN (Print)044481213X
Publication statusPublished - 1990 Jan 1
Externally publishedYes
EventThe International Narcotics Research Conference -
Duration: 1989 Jul 81989 Jul 13

Publication series

NameNew leads in opioid research: proceedings of the International Narcotics Research Conference. ICS914

Other

OtherThe International Narcotics Research Conference
Period89/7/889/7/13

ASJC Scopus subject areas

  • Medicine(all)

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  • Cite this

    Satoh, M., Ueda, H., Misawa, H., Harada, J., Nishimura, K., Katada, T., & Ui, M. (1990). Different modes of coupling of delta-opioid receptors with GTP-binding proteins in membrane preparations from guinea-pig striatum and leal myenteric plexus. In J. M. Van Ree, A. H. Mulder, V. M. Wiegant, T. B. Van Wimersma Greidanus, J. M. Van Ree, A. H. Mulder, V. M. Wiegant, & T. B. Van Wimersma Greidanus (Eds.), New leads in opioid research: proceedings of the International Narcotics Research Conference. ICS914 (pp. 297-298). (New leads in opioid research: proceedings of the International Narcotics Research Conference. ICS914). Elsevier Science Publishers B.V..