Diode-laser ablation therapy for submucosal gastric cancer using indocyanine-green solution injection to the submucosa

Takuya Hayashi, Tsunenori M.D. Arai, Shigeki Tokonabe, Harumi Itoh, Makoto Kikuchi, Shoryoku Hino, Katsunori Masuda, Hiroaki Suzuki, Hisao Tajiri, Kunihiko Hino, Yashiroh Nogami

Research output: Chapter in Book/Report/Conference proceedingConference contribution

5 Citations (Scopus)

Abstract

A 805-nm diode laser ablation therapy with indocyanine green (ICG) was studied for the endoscopic treatment of early gastric cancer. The ICG solution with 1mg/ml was administrated to the submucosa of the resected porcine and anesthetized canine stomach for the purpose of enhancing the tissue absorption to the laser light. We established complete removal of the mucosa and the submucosa with laser power of 12 or 25 watts. The proper muscle was intact because the ICG solution prevents the laser light penetration to the proper muscle. An ablated depth could be easily recognized by observing the ablated surface color. Our results showed that the combination of the 805 nm diode laser irradiation and the submucosal injection of the ICG solution might provide selective and controllable endoscopic treatment for early gastric cancer.

Original languageEnglish
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
PublisherSociety of Photo-Optical Instrumentation Engineers
Pages408-414
Number of pages7
ISBN (Print)0819423866
Publication statusPublished - 1997 Dec 1
EventLaser-Tissue Interaction VIII - San Jose, CA, USA
Duration: 1997 Feb 91997 Feb 12

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
Volume2975
ISSN (Print)0277-786X

Other

OtherLaser-Tissue Interaction VIII
CitySan Jose, CA, USA
Period97/2/997/2/12

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering

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  • Cite this

    Hayashi, T., Arai, T. M. D., Tokonabe, S., Itoh, H., Kikuchi, M., Hino, S., Masuda, K., Suzuki, H., Tajiri, H., Hino, K., & Nogami, Y. (1997). Diode-laser ablation therapy for submucosal gastric cancer using indocyanine-green solution injection to the submucosa. In Proceedings of SPIE - The International Society for Optical Engineering (pp. 408-414). (Proceedings of SPIE - The International Society for Optical Engineering; Vol. 2975). Society of Photo-Optical Instrumentation Engineers.