TY - GEN
T1 - Diode-laser ablation therapy for submucosal gastric cancer using indocyanine-green solution injection to the submucosa
AU - Hayashi, Takuya
AU - Arai, Tsunenori M.D.
AU - Tokonabe, Shigeki
AU - Itoh, Harumi
AU - Kikuchi, Makoto
AU - Hino, Shoryoku
AU - Masuda, Katsunori
AU - Suzuki, Hiroaki
AU - Tajiri, Hisao
AU - Hino, Kunihiko
AU - Nogami, Yashiroh
PY - 1997
Y1 - 1997
N2 - A 805-nm diode laser ablation therapy with indocyanine green (ICG) was studied for the endoscopic treatment of early gastric cancer. The ICG solution with 1mg/ml was administrated to the submucosa of the resected porcine and anesthetized canine stomach for the purpose of enhancing the tissue absorption to the laser light. We established complete removal of the mucosa and the submucosa with laser power of 12 or 25 watts. The proper muscle was intact because the ICG solution prevents the laser light penetration to the proper muscle. An ablated depth could be easily recognized by observing the ablated surface color. Our results showed that the combination of the 805 nm diode laser irradiation and the submucosal injection of the ICG solution might provide selective and controllable endoscopic treatment for early gastric cancer.
AB - A 805-nm diode laser ablation therapy with indocyanine green (ICG) was studied for the endoscopic treatment of early gastric cancer. The ICG solution with 1mg/ml was administrated to the submucosa of the resected porcine and anesthetized canine stomach for the purpose of enhancing the tissue absorption to the laser light. We established complete removal of the mucosa and the submucosa with laser power of 12 or 25 watts. The proper muscle was intact because the ICG solution prevents the laser light penetration to the proper muscle. An ablated depth could be easily recognized by observing the ablated surface color. Our results showed that the combination of the 805 nm diode laser irradiation and the submucosal injection of the ICG solution might provide selective and controllable endoscopic treatment for early gastric cancer.
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M3 - Conference contribution
AN - SCOPUS:0031356713
SN - 0819423866
T3 - Proceedings of SPIE - The International Society for Optical Engineering
SP - 408
EP - 414
BT - Proceedings of SPIE - The International Society for Optical Engineering
PB - Society of Photo-Optical Instrumentation Engineers
T2 - Laser-Tissue Interaction VIII
Y2 - 9 February 1997 through 12 February 1997
ER -