Direct catalytic asymmetric addition of acetonitrile to N-thiophosphinoylimines

Yuji Kawato, Naoya Kumagai, Masakatsu Shibasaki

Research output: Contribution to journalArticlepeer-review

40 Citations (Scopus)


Direct catalytic addition of acetonitrile pronucleophiles to thiophosphinoylimines is described. Soft Lewis acid-hard Brønsted base cooperative catalysis is crucial to promote this elusive carbon-carbon bond-forming reaction in an enantioselective fashion.

Original languageEnglish
Pages (from-to)11227-11229
Number of pages3
JournalChemical Communications
Issue number95
Publication statusPublished - 2013 Nov 5
Externally publishedYes

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry


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