Abstract
Objective Takotsubo cardiomyopathy (TC) mimics myocardial infarction and is well defined and known to not only Japan but also western countries. However, whether or not there are differences in the characteristics of TC between Japan and USA remains unknown. Patients Data for patients who had undergone urgent left heart catheterization for suspected acute coronary syndrome were retrospectively retrieved from Keio University School of Medicine (KUSM) database in Japan and Lahey Clinic Medical Center (LCMC) database in USA between 2002 and 2007. Results During the study period, 626 coronary angiographies were performed in KUSM and 1,880 coronary angiographies were performed in LCMC. Twelve patients in Japan and 34 patients in USA met the inclusion criteria. Mean age of patients in Japan was 75 years where 92% were women, compared to 67 years and 94% women in USA. Although the prevalence of hypertension, dyslipidemia and diabetes mellitus were similar between Japan and USA, there was a trend towards fewer patients in Japan displaying a history of coronary revascularization. Surprisingly, a family history of premature coronary artery disease (CAD) was present in 21% of USA patients, whereas no patients were present in Japan. There were no differences in the incidence of readmission for heart failure, cardiac death and TC recurrence during the follow-up period. Conclusion Patients with TC in Japan have fewer prior overt CAD and fewer family history of premature CAD, but no significant differences were found in the long-term prognosis and the recurrence rate between patients in Japan and USA.
| Original language | English |
|---|---|
| Pages (from-to) | 257-262 |
| Number of pages | 6 |
| Journal | Internal Medicine |
| Volume | 51 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - 2012 |
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Keywords
- Cardiomyopathies
- Coronary artery disease
- Heart failure
ASJC Scopus subject areas
- Internal Medicine
Cite this
Direct comparison of takotsubo cardiomyopathy between Japan and USA : 3-year follow-up study. / Maekawa, Yuichiro; Kawamura, Akio; Yuasa, Shinsuke; Nesto, Richard W.; Fukuda, Keiichi.
In: Internal Medicine, Vol. 51, No. 3, 2012, p. 257-262.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Direct comparison of takotsubo cardiomyopathy between Japan and USA
T2 - 3-year follow-up study
AU - Maekawa, Yuichiro
AU - Kawamura, Akio
AU - Yuasa, Shinsuke
AU - Nesto, Richard W.
AU - Fukuda, Keiichi
PY - 2012
Y1 - 2012
N2 - Objective Takotsubo cardiomyopathy (TC) mimics myocardial infarction and is well defined and known to not only Japan but also western countries. However, whether or not there are differences in the characteristics of TC between Japan and USA remains unknown. Patients Data for patients who had undergone urgent left heart catheterization for suspected acute coronary syndrome were retrospectively retrieved from Keio University School of Medicine (KUSM) database in Japan and Lahey Clinic Medical Center (LCMC) database in USA between 2002 and 2007. Results During the study period, 626 coronary angiographies were performed in KUSM and 1,880 coronary angiographies were performed in LCMC. Twelve patients in Japan and 34 patients in USA met the inclusion criteria. Mean age of patients in Japan was 75 years where 92% were women, compared to 67 years and 94% women in USA. Although the prevalence of hypertension, dyslipidemia and diabetes mellitus were similar between Japan and USA, there was a trend towards fewer patients in Japan displaying a history of coronary revascularization. Surprisingly, a family history of premature coronary artery disease (CAD) was present in 21% of USA patients, whereas no patients were present in Japan. There were no differences in the incidence of readmission for heart failure, cardiac death and TC recurrence during the follow-up period. Conclusion Patients with TC in Japan have fewer prior overt CAD and fewer family history of premature CAD, but no significant differences were found in the long-term prognosis and the recurrence rate between patients in Japan and USA.
AB - Objective Takotsubo cardiomyopathy (TC) mimics myocardial infarction and is well defined and known to not only Japan but also western countries. However, whether or not there are differences in the characteristics of TC between Japan and USA remains unknown. Patients Data for patients who had undergone urgent left heart catheterization for suspected acute coronary syndrome were retrospectively retrieved from Keio University School of Medicine (KUSM) database in Japan and Lahey Clinic Medical Center (LCMC) database in USA between 2002 and 2007. Results During the study period, 626 coronary angiographies were performed in KUSM and 1,880 coronary angiographies were performed in LCMC. Twelve patients in Japan and 34 patients in USA met the inclusion criteria. Mean age of patients in Japan was 75 years where 92% were women, compared to 67 years and 94% women in USA. Although the prevalence of hypertension, dyslipidemia and diabetes mellitus were similar between Japan and USA, there was a trend towards fewer patients in Japan displaying a history of coronary revascularization. Surprisingly, a family history of premature coronary artery disease (CAD) was present in 21% of USA patients, whereas no patients were present in Japan. There were no differences in the incidence of readmission for heart failure, cardiac death and TC recurrence during the follow-up period. Conclusion Patients with TC in Japan have fewer prior overt CAD and fewer family history of premature CAD, but no significant differences were found in the long-term prognosis and the recurrence rate between patients in Japan and USA.
KW - Cardiomyopathies
KW - Coronary artery disease
KW - Heart failure
UR - http://www.scopus.com/inward/record.url?scp=84856565354&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84856565354&partnerID=8YFLogxK
U2 - 10.2169/internalmedicine.51.6559
DO - 10.2169/internalmedicine.51.6559
M3 - Article
C2 - 22293799
AN - SCOPUS:84856565354
VL - 51
SP - 257
EP - 262
JO - Internal Medicine
JF - Internal Medicine
SN - 0918-2918
IS - 3
ER -