Direct proline catalyzed asymmetric α-aminooxylation of aldehydes

Yujiro Hayashi; Junichiro Yamaguchi; Kazuhiro Hibino; Mitsuru Shoji

doi:10.1016/j.tetlet.2003.09.057

Direct proline catalyzed asymmetric α-aminooxylation of aldehydes

Yujiro Hayashi, Junichiro Yamaguchi, Kazuhiro Hibino, Mitsuru Shoji

Research output: Contribution to journal › Article › peer-review

117 Citations (Scopus)

Abstract

The direct catalytic enantioselective α-aminooxylation of aldehydes has been developed using nitrosobenzene as the oxygen source and L-proline as catalyst, affording versatile α-aminooxylated aldehydes in high yield with excellent enantioselectivities.

Original language	English
Pages (from-to)	8293-8296
Number of pages	4
Journal	Tetrahedron Letters
Volume	44
Issue number	45
DOIs	https://doi.org/10.1016/j.tetlet.2003.09.057
Publication status	Published - 2003 Nov 3
Externally published	Yes

Keywords

Asymmetric reaction
Catalytic reaction
Organocatalyst
Proline
α-aminooxylation

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/j.tetlet.2003.09.057

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title = "Direct proline catalyzed asymmetric α-aminooxylation of aldehydes",

abstract = "The direct catalytic enantioselective α-aminooxylation of aldehydes has been developed using nitrosobenzene as the oxygen source and L-proline as catalyst, affording versatile α-aminooxylated aldehydes in high yield with excellent enantioselectivities.",

keywords = "Asymmetric reaction, Catalytic reaction, Organocatalyst, Proline, α-aminooxylation",

author = "Yujiro Hayashi and Junichiro Yamaguchi and Kazuhiro Hibino and Mitsuru Shoji",

note = "Funding Information: This work was supported by a Grant-in-Aid for Scientific Research on Priority Areas (A) {\textquoteleft}Exploitation of Multi-Element Cyclic Molecules{\textquoteright} from the Ministry of Education, Culture, Sports, Science and Technology, Japan.",

year = "2003",

month = nov,

day = "3",

doi = "10.1016/j.tetlet.2003.09.057",

language = "English",

volume = "44",

pages = "8293--8296",

journal = "Tetrahedron Letters",

issn = "0040-4039",

publisher = "Elsevier Limited",

number = "45",

}

TY - JOUR

T1 - Direct proline catalyzed asymmetric α-aminooxylation of aldehydes

AU - Hayashi, Yujiro

AU - Yamaguchi, Junichiro

AU - Hibino, Kazuhiro

AU - Shoji, Mitsuru

N1 - Funding Information: This work was supported by a Grant-in-Aid for Scientific Research on Priority Areas (A) ‘Exploitation of Multi-Element Cyclic Molecules’ from the Ministry of Education, Culture, Sports, Science and Technology, Japan.

PY - 2003/11/3

Y1 - 2003/11/3

N2 - The direct catalytic enantioselective α-aminooxylation of aldehydes has been developed using nitrosobenzene as the oxygen source and L-proline as catalyst, affording versatile α-aminooxylated aldehydes in high yield with excellent enantioselectivities.

AB - The direct catalytic enantioselective α-aminooxylation of aldehydes has been developed using nitrosobenzene as the oxygen source and L-proline as catalyst, affording versatile α-aminooxylated aldehydes in high yield with excellent enantioselectivities.

KW - Asymmetric reaction

KW - Catalytic reaction

KW - Organocatalyst

KW - Proline

KW - α-aminooxylation

UR - http://www.scopus.com/inward/record.url?scp=0141957357&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0141957357&partnerID=8YFLogxK

U2 - 10.1016/j.tetlet.2003.09.057

DO - 10.1016/j.tetlet.2003.09.057

M3 - Article

AN - SCOPUS:0141957357

SN - 0040-4039

VL - 44

SP - 8293

EP - 8296

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 45

ER -

Direct proline catalyzed asymmetric α-aminooxylation of aldehydes

Abstract

Keywords

ASJC Scopus subject areas

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