Discrepancy between patient-reported quality of life and the prognostic assessment of Japanese patients hospitalized with acute heart failure

Satoshi Shoji, Yasuyuki Shiraishi, Mitsuaki Sawano, Yoshinori Katsumata, Shinsuke Yuasa, Takashi Kohno, Keiichi Fukuda, John A. Spertus, Shun Kohsaka

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1 Citation (Scopus)


Patient-reported quality of life (PRQL) is a primary therapeutic target for patients with chronic heart failure (HF) and is associated with long-term prognosis. However, its utility in hospitalized HF (HHF) patients in the acute setting remains unclear. We aimed to assess the utility of PRQL (the Kansas City Cardiomyopathy Questionnaire [KCCQ]) in HHF patients and its association with long-term prognosis as well as with the clinical risk score (Get With The Guidelines-Heart Failure [GWTG-HF] risk score). PRQL was evaluated using the KCCQ in consecutive 114 HHF patients. Its association with the composite outcome of all-cause mortality or HF readmission within the first year after discharge was analyzed. Furthermore, its distribution by the clinical risk score (GWTG-HF) was evaluated using Pearson’s correlation coefficient. The median KCCQ was 34.9, but was widely distributed (interquartile range 23.7–56.8). After adjustment for known prognostic indicators, the KCCQ was not an independent predictor of the composite outcome within the first year (group with high vs. low KCCQ scores: hazard ratio, 0.67; 95% confidence interval 0.26–1.71). There was no significant correlation between the KCCQ and the GWTG-HF risk score. In conclusion, PRQL during the acute phase of HF was significantly impaired and also varied widely, irrespective of patient characteristics or severity. PRQL assessment and risk prediction for HHF patients in the acute setting seemed to provide two distinct types of information for health care providers.

Original languageEnglish
Pages (from-to)1464-1470
Number of pages7
JournalHeart and vessels
Issue number9
Publication statusPublished - 2019 Sep 13



  • Get With The Guidelines-Heart Failure risk score
  • Heart failure
  • Kansas City Cardiomyopathy Questionnaire
  • Patient-reported quality of life
  • Seattle Heart Failure Model

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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