Abstract
Patient-reported quality of life (PRQL) is a primary therapeutic target for patients with chronic heart failure (HF) and is associated with long-term prognosis. However, its utility in hospitalized HF (HHF) patients in the acute setting remains unclear. We aimed to assess the utility of PRQL (the Kansas City Cardiomyopathy Questionnaire [KCCQ]) in HHF patients and its association with long-term prognosis as well as with the clinical risk score (Get With The Guidelines-Heart Failure [GWTG-HF] risk score). PRQL was evaluated using the KCCQ in consecutive 114 HHF patients. Its association with the composite outcome of all-cause mortality or HF readmission within the first year after discharge was analyzed. Furthermore, its distribution by the clinical risk score (GWTG-HF) was evaluated using Pearson’s correlation coefficient. The median KCCQ was 34.9, but was widely distributed (interquartile range 23.7–56.8). After adjustment for known prognostic indicators, the KCCQ was not an independent predictor of the composite outcome within the first year (group with high vs. low KCCQ scores: hazard ratio, 0.67; 95% confidence interval 0.26–1.71). There was no significant correlation between the KCCQ and the GWTG-HF risk score. In conclusion, PRQL during the acute phase of HF was significantly impaired and also varied widely, irrespective of patient characteristics or severity. PRQL assessment and risk prediction for HHF patients in the acute setting seemed to provide two distinct types of information for health care providers.
| Original language | English |
|---|---|
| Journal | Heart and vessels |
| DOIs | |
| Publication status | Published - 2019 Jan 1 |
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Keywords
- Get With The Guidelines-Heart Failure risk score
- Heart failure
- Kansas City Cardiomyopathy Questionnaire
- Patient-reported quality of life
- Seattle Heart Failure Model
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
Cite this
Discrepancy between patient-reported quality of life and the prognostic assessment of Japanese patients hospitalized with acute heart failure. / Shoji, Satoshi; Shiraishi, Yasuyuki; Sawano, Mitsuaki; Katsumata, Yoshinori; Yuasa, Shinsuke; Kohno, Takashi; Fukuda, Keiichi; Spertus, John A.; Kohsaka, Shun.
In: Heart and vessels, 01.01.2019.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Discrepancy between patient-reported quality of life and the prognostic assessment of Japanese patients hospitalized with acute heart failure
AU - Shoji, Satoshi
AU - Shiraishi, Yasuyuki
AU - Sawano, Mitsuaki
AU - Katsumata, Yoshinori
AU - Yuasa, Shinsuke
AU - Kohno, Takashi
AU - Fukuda, Keiichi
AU - Spertus, John A.
AU - Kohsaka, Shun
PY - 2019/1/1
Y1 - 2019/1/1
N2 - Patient-reported quality of life (PRQL) is a primary therapeutic target for patients with chronic heart failure (HF) and is associated with long-term prognosis. However, its utility in hospitalized HF (HHF) patients in the acute setting remains unclear. We aimed to assess the utility of PRQL (the Kansas City Cardiomyopathy Questionnaire [KCCQ]) in HHF patients and its association with long-term prognosis as well as with the clinical risk score (Get With The Guidelines-Heart Failure [GWTG-HF] risk score). PRQL was evaluated using the KCCQ in consecutive 114 HHF patients. Its association with the composite outcome of all-cause mortality or HF readmission within the first year after discharge was analyzed. Furthermore, its distribution by the clinical risk score (GWTG-HF) was evaluated using Pearson’s correlation coefficient. The median KCCQ was 34.9, but was widely distributed (interquartile range 23.7–56.8). After adjustment for known prognostic indicators, the KCCQ was not an independent predictor of the composite outcome within the first year (group with high vs. low KCCQ scores: hazard ratio, 0.67; 95% confidence interval 0.26–1.71). There was no significant correlation between the KCCQ and the GWTG-HF risk score. In conclusion, PRQL during the acute phase of HF was significantly impaired and also varied widely, irrespective of patient characteristics or severity. PRQL assessment and risk prediction for HHF patients in the acute setting seemed to provide two distinct types of information for health care providers.
AB - Patient-reported quality of life (PRQL) is a primary therapeutic target for patients with chronic heart failure (HF) and is associated with long-term prognosis. However, its utility in hospitalized HF (HHF) patients in the acute setting remains unclear. We aimed to assess the utility of PRQL (the Kansas City Cardiomyopathy Questionnaire [KCCQ]) in HHF patients and its association with long-term prognosis as well as with the clinical risk score (Get With The Guidelines-Heart Failure [GWTG-HF] risk score). PRQL was evaluated using the KCCQ in consecutive 114 HHF patients. Its association with the composite outcome of all-cause mortality or HF readmission within the first year after discharge was analyzed. Furthermore, its distribution by the clinical risk score (GWTG-HF) was evaluated using Pearson’s correlation coefficient. The median KCCQ was 34.9, but was widely distributed (interquartile range 23.7–56.8). After adjustment for known prognostic indicators, the KCCQ was not an independent predictor of the composite outcome within the first year (group with high vs. low KCCQ scores: hazard ratio, 0.67; 95% confidence interval 0.26–1.71). There was no significant correlation between the KCCQ and the GWTG-HF risk score. In conclusion, PRQL during the acute phase of HF was significantly impaired and also varied widely, irrespective of patient characteristics or severity. PRQL assessment and risk prediction for HHF patients in the acute setting seemed to provide two distinct types of information for health care providers.
KW - Get With The Guidelines-Heart Failure risk score
KW - Heart failure
KW - Kansas City Cardiomyopathy Questionnaire
KW - Patient-reported quality of life
KW - Seattle Heart Failure Model
UR - http://www.scopus.com/inward/record.url?scp=85063092969&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85063092969&partnerID=8YFLogxK
U2 - 10.1007/s00380-019-01378-1
DO - 10.1007/s00380-019-01378-1
M3 - Article
C2 - 30887105
AN - SCOPUS:85063092969
JO - Heart and Vessels
JF - Heart and Vessels
SN - 0910-8327
ER -