Discrepancy between patient-reported quality of life and the prognostic assessment of Japanese patients hospitalized with acute heart failure

Satoshi Shoji, Yasuyuki Shiraishi, Mitsuaki Sawano, Yoshinori Katsumata, Shinsuke Yuasa, Takashi Kohno, Keiichi Fukuda, John A. Spertus, Shun Kosaka

Research output: Contribution to journalArticle

Abstract

Patient-reported quality of life (PRQL) is a primary therapeutic target for patients with chronic heart failure (HF) and is associated with long-term prognosis. However, its utility in hospitalized HF (HHF) patients in the acute setting remains unclear. We aimed to assess the utility of PRQL (the Kansas City Cardiomyopathy Questionnaire [KCCQ]) in HHF patients and its association with long-term prognosis as well as with the clinical risk score (Get With The Guidelines-Heart Failure [GWTG-HF] risk score). PRQL was evaluated using the KCCQ in consecutive 114 HHF patients. Its association with the composite outcome of all-cause mortality or HF readmission within the first year after discharge was analyzed. Furthermore, its distribution by the clinical risk score (GWTG-HF) was evaluated using Pearson’s correlation coefficient. The median KCCQ was 34.9, but was widely distributed (interquartile range 23.7–56.8). After adjustment for known prognostic indicators, the KCCQ was not an independent predictor of the composite outcome within the first year (group with high vs. low KCCQ scores: hazard ratio, 0.67; 95% confidence interval 0.26–1.71). There was no significant correlation between the KCCQ and the GWTG-HF risk score. In conclusion, PRQL during the acute phase of HF was significantly impaired and also varied widely, irrespective of patient characteristics or severity. PRQL assessment and risk prediction for HHF patients in the acute setting seemed to provide two distinct types of information for health care providers.

Original languageEnglish
JournalHeart and vessels
DOIs
Publication statusPublished - 2019 Jan 1

Fingerprint

Heart Failure
Quality of Life
Cardiomyopathies
Guidelines
Hospital Distribution Systems
Health Personnel
Surveys and Questionnaires
Confidence Intervals
Mortality

Keywords

  • Get With The Guidelines-Heart Failure risk score
  • Heart failure
  • Kansas City Cardiomyopathy Questionnaire
  • Patient-reported quality of life
  • Seattle Heart Failure Model

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Discrepancy between patient-reported quality of life and the prognostic assessment of Japanese patients hospitalized with acute heart failure. / Shoji, Satoshi; Shiraishi, Yasuyuki; Sawano, Mitsuaki; Katsumata, Yoshinori; Yuasa, Shinsuke; Kohno, Takashi; Fukuda, Keiichi; Spertus, John A.; Kosaka, Shun.

In: Heart and vessels, 01.01.2019.

Research output: Contribution to journalArticle

@article{4519094ea9924f18b786a01ffa36acf7,
title = "Discrepancy between patient-reported quality of life and the prognostic assessment of Japanese patients hospitalized with acute heart failure",
abstract = "Patient-reported quality of life (PRQL) is a primary therapeutic target for patients with chronic heart failure (HF) and is associated with long-term prognosis. However, its utility in hospitalized HF (HHF) patients in the acute setting remains unclear. We aimed to assess the utility of PRQL (the Kansas City Cardiomyopathy Questionnaire [KCCQ]) in HHF patients and its association with long-term prognosis as well as with the clinical risk score (Get With The Guidelines-Heart Failure [GWTG-HF] risk score). PRQL was evaluated using the KCCQ in consecutive 114 HHF patients. Its association with the composite outcome of all-cause mortality or HF readmission within the first year after discharge was analyzed. Furthermore, its distribution by the clinical risk score (GWTG-HF) was evaluated using Pearson’s correlation coefficient. The median KCCQ was 34.9, but was widely distributed (interquartile range 23.7–56.8). After adjustment for known prognostic indicators, the KCCQ was not an independent predictor of the composite outcome within the first year (group with high vs. low KCCQ scores: hazard ratio, 0.67; 95{\%} confidence interval 0.26–1.71). There was no significant correlation between the KCCQ and the GWTG-HF risk score. In conclusion, PRQL during the acute phase of HF was significantly impaired and also varied widely, irrespective of patient characteristics or severity. PRQL assessment and risk prediction for HHF patients in the acute setting seemed to provide two distinct types of information for health care providers.",
keywords = "Get With The Guidelines-Heart Failure risk score, Heart failure, Kansas City Cardiomyopathy Questionnaire, Patient-reported quality of life, Seattle Heart Failure Model",
author = "Satoshi Shoji and Yasuyuki Shiraishi and Mitsuaki Sawano and Yoshinori Katsumata and Shinsuke Yuasa and Takashi Kohno and Keiichi Fukuda and Spertus, {John A.} and Shun Kosaka",
year = "2019",
month = "1",
day = "1",
doi = "10.1007/s00380-019-01378-1",
language = "English",
journal = "Heart and Vessels",
issn = "0910-8327",
publisher = "Springer Japan",

}

TY - JOUR

T1 - Discrepancy between patient-reported quality of life and the prognostic assessment of Japanese patients hospitalized with acute heart failure

AU - Shoji, Satoshi

AU - Shiraishi, Yasuyuki

AU - Sawano, Mitsuaki

AU - Katsumata, Yoshinori

AU - Yuasa, Shinsuke

AU - Kohno, Takashi

AU - Fukuda, Keiichi

AU - Spertus, John A.

AU - Kosaka, Shun

PY - 2019/1/1

Y1 - 2019/1/1

N2 - Patient-reported quality of life (PRQL) is a primary therapeutic target for patients with chronic heart failure (HF) and is associated with long-term prognosis. However, its utility in hospitalized HF (HHF) patients in the acute setting remains unclear. We aimed to assess the utility of PRQL (the Kansas City Cardiomyopathy Questionnaire [KCCQ]) in HHF patients and its association with long-term prognosis as well as with the clinical risk score (Get With The Guidelines-Heart Failure [GWTG-HF] risk score). PRQL was evaluated using the KCCQ in consecutive 114 HHF patients. Its association with the composite outcome of all-cause mortality or HF readmission within the first year after discharge was analyzed. Furthermore, its distribution by the clinical risk score (GWTG-HF) was evaluated using Pearson’s correlation coefficient. The median KCCQ was 34.9, but was widely distributed (interquartile range 23.7–56.8). After adjustment for known prognostic indicators, the KCCQ was not an independent predictor of the composite outcome within the first year (group with high vs. low KCCQ scores: hazard ratio, 0.67; 95% confidence interval 0.26–1.71). There was no significant correlation between the KCCQ and the GWTG-HF risk score. In conclusion, PRQL during the acute phase of HF was significantly impaired and also varied widely, irrespective of patient characteristics or severity. PRQL assessment and risk prediction for HHF patients in the acute setting seemed to provide two distinct types of information for health care providers.

AB - Patient-reported quality of life (PRQL) is a primary therapeutic target for patients with chronic heart failure (HF) and is associated with long-term prognosis. However, its utility in hospitalized HF (HHF) patients in the acute setting remains unclear. We aimed to assess the utility of PRQL (the Kansas City Cardiomyopathy Questionnaire [KCCQ]) in HHF patients and its association with long-term prognosis as well as with the clinical risk score (Get With The Guidelines-Heart Failure [GWTG-HF] risk score). PRQL was evaluated using the KCCQ in consecutive 114 HHF patients. Its association with the composite outcome of all-cause mortality or HF readmission within the first year after discharge was analyzed. Furthermore, its distribution by the clinical risk score (GWTG-HF) was evaluated using Pearson’s correlation coefficient. The median KCCQ was 34.9, but was widely distributed (interquartile range 23.7–56.8). After adjustment for known prognostic indicators, the KCCQ was not an independent predictor of the composite outcome within the first year (group with high vs. low KCCQ scores: hazard ratio, 0.67; 95% confidence interval 0.26–1.71). There was no significant correlation between the KCCQ and the GWTG-HF risk score. In conclusion, PRQL during the acute phase of HF was significantly impaired and also varied widely, irrespective of patient characteristics or severity. PRQL assessment and risk prediction for HHF patients in the acute setting seemed to provide two distinct types of information for health care providers.

KW - Get With The Guidelines-Heart Failure risk score

KW - Heart failure

KW - Kansas City Cardiomyopathy Questionnaire

KW - Patient-reported quality of life

KW - Seattle Heart Failure Model

UR - http://www.scopus.com/inward/record.url?scp=85063092969&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85063092969&partnerID=8YFLogxK

U2 - 10.1007/s00380-019-01378-1

DO - 10.1007/s00380-019-01378-1

M3 - Article

C2 - 30887105

AN - SCOPUS:85063092969

JO - Heart and Vessels

JF - Heart and Vessels

SN - 0910-8327

ER -