Abstract
Puberty is the continuous maturation of growth and development to attain full sexual development and fertility by the hypothalamic-pituitary-gonadal. axis and other complex endocrine systems. Although the physiology and molecular mechanism of normal puberty are not completely understood, we have made great progress in the management and treatment of disorders of pubertal development such as precocious puberty and delayed puberty. Moreover, the gene abnormalities of disorders of puberta l disorders have been elucidated one after another. This chapter mainly focuses clinical issues and single gene disorders of disorders of pubertal development.
| Original language | English |
|---|---|
| Title of host publication | Principles of Molecular Medicine |
| Publisher | Humana Press |
| Pages | 453-465 |
| Number of pages | 13 |
| ISBN (Print) | 9781588292025 |
| DOIs | |
| Publication status | Published - 2006 Dec 1 |
Keywords
- Congenital adrenal hyperplasia
- Kallmann syndrome
- Klinefelter syndrome
- McCune-Albright syndrome
- Turner syndrome
- constitutional delay of puberty
- delayed puberty
- familial male limited precocious puberty
- hypergonadotropic hypogonadism
- hypogo-nadotropic hypogonadism
- precocious puberty
- premature
- premature pubarche
- puberty
- thelarche
ASJC Scopus subject areas
- Medicine(all)