Distribution of Lymph Node Metastasis and Clinical Validity of Gastric Tube Reconstruction in Lower Thoracic Esophageal Squamous Cell Carcinoma with Gastric Invasion

Satoru Matsuda, Yasuhiro Tsubosa, Masahiro Niihara, Hiroshi Sato, Katsushi Takebayashi, Keisuke Kawamorita, Keita Mori, Takahiro Tsushima, Hirofumi Yasui, Hiroya Takeuchi, Yuukou Kitagawa

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Abstract

Results: Of 79 patients, the distribution of pretreatment gastric invasion was Gr 0, 1, and 2 in 57, 15, and 7 patients, respectively. All patients underwent subtotal esophagectomy with gastric tube reconstruction. There was no significant difference in the number of abdominal LN metastases among groups. In survival analysis, the location of the distal end of the tumor was not a predictive factor for postoperative recurrence. Regarding patterns of recurrence, in patients with gastric invasion, there was no remarkable increase in the frequency of recurrence in the abdominal LNs or the regional LNs around the gastric tube.

Conclusions: Pretreatment gastric invasion did not significantly influence abdominal LN metastasis and postoperative recurrence. In patients with esophageal SCC at the lower thoracic esophagus with gastric invasion, subtotal esophagectomy with gastric tube reconstruction might be a valid surgical procedure.

Background: The distribution of lymph node (LN) metastases of esophageal squamous cell carcinoma (SCC) with gastric invasion remains unclear. The purpose of this study was to clarify the relationship between gastric invasion and abdominal LN metastasis in patients with esophageal SCC. Furthermore, the clinical validity of gastric tube reconstruction for those with gastric invasion was investigated.

Methods: Patients who underwent subtotal esophagectomy at our institution were reviewed. Gastric invasion was evaluated with pretreatment upper gastrointestinal endoscopy and classified into 3 groups: no invasion, Gr 0; slight invasion (0–19 mm), Gr 1; and massive invasion (20 mm or longer), Gr 2. The correlations between gastric invasion, the number of abdominal LN metastases, and postoperative recurrence were investigated.

Original languageEnglish
Pages (from-to)617-623
Number of pages7
JournalAnnals of Surgical Oncology
Volume22
Issue number2
DOIs
Publication statusPublished - 2014

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Stomach
Thorax
Lymph Nodes
Neoplasm Metastasis
Esophagectomy
Recurrence
Esophageal Squamous Cell Carcinoma
Gastrointestinal Endoscopy
Survival Analysis
Esophagus

ASJC Scopus subject areas

  • Surgery
  • Oncology

Cite this

Distribution of Lymph Node Metastasis and Clinical Validity of Gastric Tube Reconstruction in Lower Thoracic Esophageal Squamous Cell Carcinoma with Gastric Invasion. / Matsuda, Satoru; Tsubosa, Yasuhiro; Niihara, Masahiro; Sato, Hiroshi; Takebayashi, Katsushi; Kawamorita, Keisuke; Mori, Keita; Tsushima, Takahiro; Yasui, Hirofumi; Takeuchi, Hiroya; Kitagawa, Yuukou.

In: Annals of Surgical Oncology, Vol. 22, No. 2, 2014, p. 617-623.

Research output: Contribution to journalArticle

Matsuda, Satoru ; Tsubosa, Yasuhiro ; Niihara, Masahiro ; Sato, Hiroshi ; Takebayashi, Katsushi ; Kawamorita, Keisuke ; Mori, Keita ; Tsushima, Takahiro ; Yasui, Hirofumi ; Takeuchi, Hiroya ; Kitagawa, Yuukou. / Distribution of Lymph Node Metastasis and Clinical Validity of Gastric Tube Reconstruction in Lower Thoracic Esophageal Squamous Cell Carcinoma with Gastric Invasion. In: Annals of Surgical Oncology. 2014 ; Vol. 22, No. 2. pp. 617-623.
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AU - Niihara, Masahiro

AU - Sato, Hiroshi

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AU - Kawamorita, Keisuke

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