TY - JOUR
T1 - Diversity of clinical isolates of Entamoeba histolytica in Japan
AU - Nozaki, Tomoyoshi
AU - Kobayashi, Seiki
AU - Takeuchi, Tsutomu
AU - Haghighi, Ali
N1 - Funding Information:
This work was supported by a grant for research on emerging and re-emerging infectious diseases from the Ministry of Health, Labour, and Welfare of Japan.
PY - 2006/2
Y1 - 2006/2
N2 - In Japan, amebiasis is domestically transmitted by two major populations: male homosexuals and mentally handicapped persons, which is remarkably different from most other developed countries where Entamoeba dispar infection is predominantly observed. Here we briefly summarize epidemiology of amebiasis in Japan. We also review our current understanding of the diversity of Entamoeba histolytica clinical isolates in Japan, based on polymorphic genetic markers, clinical representations, and in vivo virulence, using an animal model.
AB - In Japan, amebiasis is domestically transmitted by two major populations: male homosexuals and mentally handicapped persons, which is remarkably different from most other developed countries where Entamoeba dispar infection is predominantly observed. Here we briefly summarize epidemiology of amebiasis in Japan. We also review our current understanding of the diversity of Entamoeba histolytica clinical isolates in Japan, based on polymorphic genetic markers, clinical representations, and in vivo virulence, using an animal model.
KW - Amebiasis
KW - Epidemiology
KW - Heterogeneity
KW - Mentally handicapped persons
KW - Sexually transmitted disease
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U2 - 10.1016/j.arcmed.2005.09.010
DO - 10.1016/j.arcmed.2005.09.010
M3 - Review article
C2 - 16380332
AN - SCOPUS:29344474449
SN - 0188-4409
VL - 37
SP - 276
EP - 278
JO - Archives of Medical Research
JF - Archives of Medical Research
IS - 2
ER -
