DNA Aptamer-Linked Structural-Color Hydrogel for Repeatable Biochemical Sensing

Tomoki Hayashi, Masahiro Takinoue, Hiroaki Onoe

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

This paper describes a DNA aptamer-linked structural-color hydrogel sensor that can quantitatively and repeatably detect biochemical substances through visual information without any specific equipment. The initial color of structural-color hydrogel could be adjusted by controlling the concentration of the colloidal silica particle. We co-polymerized a DNA aptamer that specifically binds to silver ions into acrylamide hydrogel and evaluated its quantitative shrinking response to silver acetate solution. In addition, we succeeded in initializing our DNA aptamer hydrogel sensor by heating, indicating that our chemical sensor could repeatably measure the target chemical substance for the long term. We believe that our structural-color biochemical sensor could be applied to various routine monitoring such as healthcare diagnosis and water safety.

Original languageEnglish
Title of host publication2019 20th International Conference on Solid-State Sensors, Actuators and Microsystems and Eurosensors XXXIII, TRANSDUCERS 2019 and EUROSENSORS XXXIII
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages582-585
Number of pages4
ISBN (Electronic)9781728120072
DOIs
Publication statusPublished - 2019 Jun
Event20th International Conference on Solid-State Sensors, Actuators and Microsystems and Eurosensors XXXIII, TRANSDUCERS 2019 and EUROSENSORS XXXIII - Berlin, Germany
Duration: 2019 Jun 232019 Jun 27

Publication series

Name2019 20th International Conference on Solid-State Sensors, Actuators and Microsystems and Eurosensors XXXIII, TRANSDUCERS 2019 and EUROSENSORS XXXIII

Conference

Conference20th International Conference on Solid-State Sensors, Actuators and Microsystems and Eurosensors XXXIII, TRANSDUCERS 2019 and EUROSENSORS XXXIII
CountryGermany
CityBerlin
Period19/6/2319/6/27

Keywords

  • Biosensor
  • DNA Aptamer
  • Diagnosis
  • Hydrogel
  • Structural-Color

ASJC Scopus subject areas

  • Process Chemistry and Technology
  • Spectroscopy
  • Electrical and Electronic Engineering
  • Mechanical Engineering
  • Electronic, Optical and Magnetic Materials
  • Control and Optimization
  • Instrumentation

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  • Cite this

    Hayashi, T., Takinoue, M., & Onoe, H. (2019). DNA Aptamer-Linked Structural-Color Hydrogel for Repeatable Biochemical Sensing. In 2019 20th International Conference on Solid-State Sensors, Actuators and Microsystems and Eurosensors XXXIII, TRANSDUCERS 2019 and EUROSENSORS XXXIII (pp. 582-585). [8808609] (2019 20th International Conference on Solid-State Sensors, Actuators and Microsystems and Eurosensors XXXIII, TRANSDUCERS 2019 and EUROSENSORS XXXIII). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/TRANSDUCERS.2019.8808609